Results 51 to 60 of about 179,604 (239)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Private Rooms in Peer-to-Peer Accommodation: Employing Machine Learning to Determine Revenue Drivers

European Management Studies
Purpose: The goal of this study was to identify the performance determinants of private rooms offered via peer-to-peer accommodation (P2PA) platforms.
Ewa E. Kiczmachowska
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Price fairness, guest emotions, satisfaction, and behavioral intentions in peer to peer accommodation sector

Journal of Global Business Insights, 2018
The aim of this study is to examine the impact of price fairness on guest emotions, satisfaction and behavioral intentions in Malaysian P2P accommodation sector.
Laiba Ali, Wong Yee, Ng Imm, Muhammad Akhtar   +3 more
doaj   +1 more source

Congestion management under peer-to-peer energy trading scheme among microgrids through cooperative game

Energy Reports, 2022
The peer-to-peer (P2P) energy trading among microgrids (MGs) can promote the renewable energy accommodation of network while maximizing the benefits of their own.
Xiaoyu Wang, Tao Xu, Yunfei Mu, Zibo Wang, Youjun Deng, Tao Zhang, Qian Jiang, Yaqing Zhang, Hongjie Jia   +8 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Person-centred advocacy for people with dementia - a personal account [PDF]

, 2007
In the first of two articles on advocacy for people with dementia, Mike Fox and Lesley Wilson describe an advocacy project based in a residential home and consider the issues and themes that ...
Fox, M, Wilson, L
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Impacts of the Peer-To-Peer Market on Tourist Accommodation on the Balearic Islands of Mallorca and Menorca

Island Studies Journal, 2020
Using the Balearic Islands of Mallorca and Menorca as case studies, this research identifies the patterns of development in the peer-to-peer market for tourist accommodation in the islands.
Beatriz Benítez-Aurioles
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source