Results 51 to 60 of about 1,447,355 (302)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Peer relationships in kindergarten [PDF]

, 2019
Rođenjem djeteta počinje njegova socijalizacija. Tijekom odrastanja dijete se polako odvaja od roditeljske sigurnosti i njegova se socijalna mreža postupno širi do ostalih članova obitelji, drugih odraslih pa sve do vršnjaka koje upoznaje u dječjem ...
Šiškić, Terezija
core  

Consistency and Trust in Peer Data Exchange Systems

, 2016
We propose and investigate a semantics for "peer data exchange systems" where different peers are related by data exchange constraints and trust relationships. These two elements plus the data at the peers' sites and their local integrity constraints are
Bertossi, Leopoldo, Bravo, Loreto
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Links Between Attention-Deficit/Hyperactivity Disorder Symptoms, Peer Relationships and Mental Health Outcomes in Western Australian Youth

Children
Peer relationships are critical in the development of positive mental health during childhood and adolescence. Attention-deficit/hyperactivity disorder (ADHD) symptoms can adversely affect the development of positive peer relationships, and thus, have ...
Carolyn Maxwell, Stephen Houghton, Elaine Chapman   +2 more
doaj   +1 more source

Emotion regulation among 4–6 year-old children and its association with their peer relationships in Jordan

Frontiers in Psychology, 2023
Specific characteristics and competencies are required for maintaining peer relationships, and this study hypothesizes that emotion regulation is one of the competencies.
Amani F. Qashmer
doaj   +1 more source

UK Breastfeeding Helpline support: An investigation of influences upon satisfaction [PDF]

, 2012
Background Incentive or reward schemes are becoming increasingly popular to motivate healthy lifestyle behaviours. In this paper, insights from a qualitative and descriptive study to investigate the uptake, impact and meanings of a breastfeeding ...
A Dean, A McEwen, Chris J Sutton, CL Dennis, CL Dennis, CL Dennis, CL Dennis, E McColl, Fiona Dykes, GD Meglio, Gill Thomson, GJ Coman, H Gilbert, J Boddy, J Dale, JM Lim, K Shandley, LB Chamberlain, Nicola Crossland, P Hugo, PA Janssen, PM Rutter, RA Bryant, RJ Reese, SF Wang, T Takabayashi, UK Young, V Schmied   +27 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Peer Mentors and Writing Center Tutors: What our collaborations taught us about serving the SJSU Freshmen Students [PDF]

, 2007
The Library Outpost, a satellite office of the campus’s Dr. Martin Luther King Jr. Library, seeks ways to reach out to First Year students who are new to writing research papers.
Bruce, Robert, Cabrera, Peggy, Howard, Francis E   +2 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source