Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Technology-enabled sexual health promotion for individuals with intellectual and developmental disabilities: protocol for a scoping review. [PDF]
P James C +4 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Integrated model of Student Standardized Patients and peer assessment enhances SOAP note proficiency in obstetrics and gynecology residency. [PDF]
Chen P +6 more
europepmc +1 more source
"No Words Needed": Results of a Survey on How Parents of Children With Neurodevelopmental Disorders Perceive (In)formal Peer Support. [PDF]
Verkooijen M +5 more
europepmc +1 more source
Peer victimization and physical activity: the mediating role of self-esteem and physical self-concept. [PDF]
Guo Y +6 more
europepmc +1 more source
The approaches, theories, models, frameworks, and methods in designing toolkits to support healthcare providers in health behaviour change: A scoping review protocol. [PDF]
Scandiffio J +8 more
europepmc +1 more source

