Results 91 to 100 of about 3,286,432 (344)

Utility of shaking chills as a diagnostic sign for bacteremia in adults: a systematic review and meta-analysis

open access: yesBMC Medicine
Background Accurate prediction of bacteremia is essential for guiding blood culture collection and optimal antibiotic treatment. Shaking chills, defined as a subjective chill sensation with objective body shivering, have been suggested as a potential ...
Tetsuro Aita   +6 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Reviewing Peer Review [PDF]

open access: yesJournal of the American Heart Association, 2021
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Efficacy of a meal sequence in patients with type 2 diabetes: a systematic review and meta-analysis

open access: yesBMJ Open Diabetes Research & Care, 2022
Yuki Kataoka   +3 more
doaj   +1 more source

Who Is (Likely) Peer-Reviewing Your Papers? A Partial Insight into the World’s Top Reviewers

open access: yesPublications, 2019
Scientific publishing is experiencing unprecedented growth in terms of outputs across all fields. Inevitably this creates pressure throughout the system on a number of entities.
Francesco Pomponi   +2 more
doaj   +1 more source

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