Results 91 to 100 of about 3,169,769 (303)

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

FEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Moving peer review transparency from process to praxis

Insights: The UKSG Journal, 2019
Scholarly publications often work to provide transparency of peer-review processes, posting policy information to their websites as suggested by the Committee on Publication Ethics’ (COPE) 'Principles of Transparency and Best Practice in Publishing'. Yet
Emily Ford
doaj   +1 more source

Collaborative Learning Through Formative Peer Review With Technology

, 2014
This paper describes a collaboration between a mathematician and a compositionist who developed a sequence of collaborative writing assignments for calculus. This sequence of developmentally-appropriate assignments presents peer review as a collaborative
Eaton, Carrie Diaz, Wade, Stephanie
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Efficacy of a meal sequence in patients with type 2 diabetes: a systematic review and meta-analysis

BMJ Open Diabetes Research & Care, 2022
Yuki Kataoka, Jun Watanabe, Yukiko Okami, Hideki Tsunoda   +3 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Peer Review #2 of "Impact of work environment perceptions and communication satisfaction on the intention to quit: an empirical analysis of nurses in Saudi Arabia (v0.1)"

, 2021
Abdulaziz M. Alsufyani, Khalid A. Almalki, Yasir Alsufyani, Sayer Aljuaid, Abeer Almutairi, Bandar Alsufyani, Abdullah Alshahrani, Omar Ghazi Baker, Ahmad E. Aboshaiqah   +8 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Peer Feedback Tool for Clinical Teaching

MedEdPORTAL, 2011
This resource is a peer feedback tool for clinical teaching, designed to provide assessment through peer observation of effective teaching behaviors.
Elisa Zenni, Heather Hageman, Janet Hafler, Maryellen Gusic   +3 more
doaj   +1 more source

Efetivação da open peer review frente aos editores do Portal de Periódicos da Universidade Federal da Paraíba

, 2021
Kleisson Lainnon Nascimento da Silva, Joana Coeli Ribeiro Garcia, Maria das Graças Targino   +2 more
openalex   +2 more sources