Results 91 to 100 of about 3,030,229 (330)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Anomalies in the peer-review system: A case study of the journal of High Energy Physics

open access: yes, 2016
Peer-review system has long been relied upon for bringing quality research to the notice of the scientific community and also preventing flawed research from entering into the literature.
Ganguly, Niloy   +3 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Efficacy of a meal sequence in patients with type 2 diabetes: a systematic review and meta-analysis

open access: yesBMJ Open Diabetes Research & Care, 2022
Yuki Kataoka   +3 more
doaj   +1 more source

peering into peer review

open access: yesSociologia, 2010
This article examines the social mechanisms behind peer review and provides a complementary view to Michèle Lamont’s book, How Professors Think. It emphasizes the need for outlook review of the entire process of evaluation in science in more general terms and suggests the added value of modelling to investigate it.
openaire   +2 more sources

A Review of Peer Relationships and Friendships in Youth With ADHD [PDF]

open access: yes, 2015
Objective: The purpose of this essay is to examine peer relationships in youth with ADHD and to review current peer functioning interventions. Method: The studies included in this review were identified using the following search terms: “attention ...
Gardner, Denise M., Gerdes, Alyson C.
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Increasing the degree of acceptability for chatbots in technical support systems for educational sector by using ML and semantic web

open access: yesAlexandria Engineering Journal
Work on digital transformation is one of the main features of the fourth economic revolution, which tends to benefit from technology in various aspects of life.
Adel A. Bahaddad
doaj  

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