Results 111 to 120 of about 994,354 (266)

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Words Matter: Peer Review as a Failing Safeguard

open access: yesPerspectives on Terrorism, 2013
Peer review is intended to support the quality and standards of academic work.  The peer review process has been questioned recently in a number of different arenas.  Source reliability and information credibility can be a problem when an ...
Tom Quiggin
doaj  

Guidelines for writing and reviewing software in computer algebra [PDF]

open access: yesarXiv
The advent of computers has allowed mathematicians to do increasingly more difficult computations that used to be practically impossible. Peer reviewers will seldom look at any code attached to a math paper, however. In this article, we advocate for a software peer-reviewing process and will discuss some best practices for reviewers on how to peer ...
arxiv  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Peer Comment: Films, digs and death: a review of the Project Eliseg videos

open access: yesInternet Archaeology, 2015
Peer comment on Vlog to Death: Project Eliseg's Video-Blogging by Joseph Tong, Suzanne Evans, Howard Williams, Nancy Edwards and Gary Robinson .
Ben Marwick
doaj   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

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