Results 91 to 100 of about 13,359,499 (297)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Peer review: types, pitfalls and controversies

Bangladesh Journal of Bioethics
Peer review has been adopted by most journals to evaluate the quality of submitted manuscripts, for which peer reviewers aim to provide a critical, independent and unbiased assessment. Peer review is ever evolving, with no single peer review system being
Wilfred C. G. Peh
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Reviewing Peer Review

Philippine Journal of Otolaryngology Head and Neck Surgery, 2014
Peer review is widely accepted as the hallmark of scholarly, scientific publication. It helps journal editors determine whether research conclusions are justified and “new,” gives them an idea of the potential or actual significance of a work1 and adds a
José Florencio F. Lapeña
doaj   +1 more source

Logotipo del Open Peer Review Module [PDF]

, 2016
https://github.com/arvoConsultores/Open-Peer-Review-Module/wikihttp://www.openscholar.org.uk/developing-the-first-open-peer-review-module-for-institutional-repositories/The Open Peer Review Module Consortium include: Open Scholar, Arvo Consultores (a ...
Oficina Técnica de DIGITAL.CSIC, Open Peer Review Module Consortium, Román-Molina, Juan   +2 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Group identity and peer relations: A longitudinal study of group identity, perceived peer acceptance and friendships amongst ethnic minority English children [PDF]

, 2011
This research examined whether peer relationships amongst ethnic minority status children reflect the social groups to which children belong and the degree to which they identify with these groups.
Anick Landau (16053803), Brown, Rupert, Dennis Nigbur, Dominique Le Touze (16053806), Rupert Brown, Philipp Jugert (16057334), Rosa Hossain (16053800), Cameron, Lindsey, Watters, Charles, Jugent, Philipp, Charles Watters (4461469), Adam Rutland, Rutland, Adam, Landau, Anick, LeTouze, Dominique, Lindsey Cameron (7537682), Jugert, Philipp, Dennis Nigbur (16053797), Anick Landau, Hossain, Rosa, Le Touze, Dominique, Charles Watters (12529190), Lindsey Cameron, Adam Rutland (9160025), Philipp Jugert, Nigbur, Dennis, Rosa Hossain, Rupert Brown (4461505), Charles Watters, Dominique Le Touze, Rutland, A., Brown, R., Nigbur, D., Watters, C., Cameron, L., Jugert, P., Hossain, R., Le Touze, D., Landau, A.   +38 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source