Results 131 to 140 of about 219,887 (261)
Words Matter: Peer Review as a Failing Safeguard
Peer review is intended to support the quality and standards of academic work. The peer review process has been questioned recently in a number of different arenas. Source reliability and information credibility can be a problem when an ...
Tom Quiggin
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Manufacturing defects are errors in product design or production that can cause harm, injury, or fatality to consumers. These defects are relevant to knowledge production in academic manuscript writing.
Paul Svongoro +2 more
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Soft peer review: social software and distributed scientific evaluation
The debate on the prospects of peer-review in the Internet age and the increasing criticism leveled against the dominant role of impact factor indicators are calling for new measurable criteria to assess scientific quality. Usage-based metrics offer a
Taraborelli, D.
core
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Plan BAdolescents have always been exposed to peer influence, but the kinds of peer influence that they encounter have changed tremendously in the past years.
Howard, Nicole Marie
core

