Results 31 to 40 of about 3,030,229 (330)

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

How Long is the Peer Review Process for Journal Manuscripts? A Case Study on Angewandte Chemie International Edition

open access: yesCHIMIA, 2010
One of the most frequently raised criticisms of the review process for manuscripts is that the length of time between submission of a manuscript and the editorial decision is overly long.
Lutz Bornmann, Hans-Dieter Daniel
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

A Preliminary Study on Legitimacy Identification Standards for Unconventional Treatment Technologies in Traditional Chinese Medicine

open access: yesDigital Chinese Medicine, 2020
Compared with western medicine with objective and standardized theories, traditional Chinese medicine (TCM) places more emphasis on subjective thinking.
Liu Da-Hua, Cao Shu-Hua
doaj  

In Appreciation: A Thank-You to Our Industrious Reviewers

open access: yesMarshall Journal of Medicine, 2022
The reputation of the Marshall Journal of Medicine depends on the authors' contribution; however, the standard of the Journal's level of excellence is also a consequence of the efforts of expert peer reviewers.
Darshana T. Shah
doaj   +1 more source

On Peer Review [PDF]

open access: yesJournal of Speech, Language, and Hearing Research, 2016
Purpose This letter briefly reviews ideas about the purpose and benefits of peer review and reaches some idealistic conclusions about the process. Method The author uses both literature review and meditation born of long experience. Results
openaire   +5 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Alternative to Peer Review?

open access: yesScience, 1981
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openaire   +13 more sources

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