Results 51 to 60 of about 3,185,750 (289)

Long Dan Xie Gan Formula Granule Promotes Pro-Inflammatory Cytokine Expression in Female Guinea Pigs with Recurrent Genital Herpes

Digital Chinese Medicine, 2018
: Objective To explore the effects of Long Dan Xie Gan formula granule (LDXGFG) on regulation of pro-inflammatory cytokines in female guinea pigs with recurrent genital herpes (herpes simplex virus 2, HSV-2).Methods Levels of pro-inflammatory cytokines ...
Lin KUANG, En-Hui HUANG, Qing-Hu HE, Shao-Wu CHENG, Xiao-Dan LIU   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Constitution Identification System for Traditional Chinese Medicine (TCM) Based on Correlation Between TCM Constitution and Physical Examination Indices

Digital Chinese Medicine, 2018
: Objective Identification of one’s constitution based on a combination of features and back propagation neural network theory is needed in modern medicine and traditional Chinese medicine (TCM).
Yue Luo, Bing Lin, Chuan-Biao Wen, Jie-Lin He   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Pediatric Orthopaedic Clinical Peer-review Triggers and Ongoing Professional Practice Evaluation (OPPE) Metrics: An Ohio Statewide Consensus

Journal of the Pediatric Orthopaedic Society of North America
Background: Two critical mechanisms to measure competency in pediatric orthopaedic surgery are case-based clinical peer review and ongoing professional practice evaluation (OPPE). However, we currently lack a standard set of triggers or metrics to inform
Julie B. Samora, MD, PhD, Kevin Baker, RN, Kerwyn Jones, MD, Michael Vish, MD, Susan P. Tourner, MD, Michael Vossmeyer, MD, Nichole Liston, RN, Todd F. Ritzman, MD, Michael T. Bigham, MD, MBA   +8 more
doaj   +1 more source

In Appreciation: A Thank-You to Our Industrious Reviewers

Marshall Journal of Medicine, 2022
The reputation of the Marshall Journal of Medicine depends on the authors' contribution; however, the standard of the Journal's level of excellence is also a consequence of the efforts of expert peer reviewers.
Darshana T. Shah
doaj   +1 more source

EU and OECD benchmarking and peer review compared [PDF]

, 2009
Benchmarking and peer review are essential elements of the so-called EU open method of coordination (OMC) which has been contested in the literature for lack of effectiveness.
Groenendijk, Nico
core   +1 more source

Citation and peer review of data: moving towards formal data publication [PDF]

, 2011
This paper discusses many of the issues associated with formally publishing data in academia, focusing primarily on the structures that need to be put in place for peer review and formal citation of datasets.
Callaghan, S, Jones, C., Lawrence, Bryan, Matthews, B., Pepler, S.   +4 more
core   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Peer Feedback Tool for Lectures & Small-Group Teaching

MedEdPORTAL, 2011
This resource is a teaching assessment tool designed to provide faculty members with information about the quality of their teaching based on peer observation.
Maria Blanco, Carol Capello, Maryellen Gusic, Wayne McCormack, Janet Hafler   +4 more
doaj   +1 more source