Results 61 to 70 of about 219,887 (261)

Maintaining Live Discussion in Two-Stage Open Peer Review

open access: yesFrontiers in Computational Neuroscience, 2012
Open peer review has been proposed for a number of reasons, in particular, for increasing the transparency of the article selection process for a journal, and for obtaining a broader basis for feedback to the authors and for the acceptance decision.
Erik eSandewall, Erik eSandewall
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Developing a cognitive conservation model for the management of Malaysian birders' behavior toward birds

open access: yesFrontiers in Sustainable Tourism
IntroductionBirdwatching as a subcategory of ecotourism can create recreational disturbance. This research aims to assess two main goals: firstly, the effects of the frequency of participation (FOP) of Malaysian birders as moderators on the constructs of
Marjan Jafarpour   +4 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

From concept to regulation: OECD’s role in the development of the DNT in vitro battery

open access: yesFrontiers in Toxicology
Chemical exposure during critical stages of nervous system development can lead to adverse neurotoxic effects, known as developmental neurotoxicity (DNT).
Magdalini Sachana   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Report of an independent peer review of A forest management strategy for the proposed Coquille Forest submitted to the Coquille Indian Tribe by the Independent Scientific Advisory Team (ISAT)

open access: yes, 1995
"[T]he [Coquille Indian] Tribe requested that the State of Oregon assemble a team of independent scientists to peer review the forest management strategy proposed by the ISAT.

core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Professional Competence Peer Review and Quality Assurance in England and Wales and in Scotland

open access: yes, 2008
Peer review has emerged as a method of assessing the work of legal aid lawyers in the United Kingdom. The authors show how testing different methods led to review of files emerging as the most effective means of peer review.
Sherr, Avrom, Paterson, Alan
core   +1 more source

Blockchain-enabled KYC integration for CLV optimization with robust M-Estimation and IRLS method

open access: yesICT Express
This research introduces an innovative approach in implementing Know Your Customer (KYC) on blockchain technology as a means of using data, hybrid robust m-estimation, and the iteratively reweighted less squares (IRLS) method to optimize CLV data.
Marischa Elveny   +3 more
doaj   +1 more source

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