Results 131 to 140 of about 946,633 (311)
Peer-Allocated Instant Response (PAIR): Computational Allocation of Peer Tutors in Learning Communities [PDF]
This paper proposes a computational model for the allocation of fleeting peer tutors in a community of learners: a student\'s call for support is evaluated by the model in order to allocate the most appropriate peer tutor.
Wim Westera
core
Students developing critical evaluation skills as part of peer and self assessment [PDF]
, 2007 This article was first published in the Wolverhampton Intellectual Repository and E-Theses (WIRE). There is no printed version.This CELT project is part of the University’s commitment to widening participation.
Rogers-Harris, Clair, Mycroft, Lesley
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Efficacy of a meal sequence in patients with type 2 diabetes: a systematic review and meta-analysis
BMJ Open Diabetes Research & Care, 2022 Yuki Kataoka +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source