Results 151 to 160 of about 2,675,624 (254)

Understanding the roles and experiences of mental health peer support workers in England: a qualitative interview study. [PDF]

BMC Psychiatry
Cooper RE, Lyons N, Jeffreys S, Jeynes T, Nicholls V, Foye U, Shah P, Mitchell L, Machin K, Chipp B, Grundy A, Pemovska T, Ahmed N, Appleton R, Repper J, Lloyd-Evans B, Simpson A, Johnson S.   +17 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

What Youth Write About and Seek in an Anonymized Online Peer Support Forum: Insights from India. [PDF]

Int J Environ Res Public Health
Tripathi R, Karishiddimath A, Sengupta P, Khatri K, Kv L, Jose JT, Idicula AE, Srikanth TK, Mehrotra S.   +8 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Digital Peer Support to Increase Walking Among Older Adults: Cluster Randomized Trial.

J Med Internet Res
Nakagomi A, Abe N, Ueno T, Izuka G, Kawasaki Y, Kondo K.   +5 more
europepmc   +1 more source

Mental health peer support relationship: a realist informed qualitative meta synthesis. [PDF]

BMJ Open
Hackmann C, Green A, Pease R, Clegg I, Handley M.   +4 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Strengthening the Culture of Well-Being in Rural Hospitals Through RISE Peer Support. [PDF]

Healthcare (Basel)
Malik M, Yenokyan G, Michtalik H, Miller J, Connors C, Weston CM, Weeks K, Hu W, Norvell M, Wu AW.   +9 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source