Results 11 to 20 of about 2,675,624 (254)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra +3 more
wiley +1 more source
The integration of grid and peer-to-peer to support scientific collaboration [PDF]
, 2004 There have been a number of e-Science projects which address the issues of collaboration within and between scientific communities. Most effort to date focussed on the building of the Grid infrastructure to enable the sharing of huge volume of ...
Dew, P.M., Lau, L.M.S., Pham, T.V.
core
Peer observation : a tool for continuing professional development [PDF]
, 2007 Peer observation has been advocated as a means of monitoring and improving the quality of teaching within Higher Education, whilst peer support and review have been used to provide feedback and monitoring within the clinical context.
Davys, D, Jones, V
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender +17 more
wiley +1 more source
Peer Support for Addiction in the Inpatient Setting [PDF]
, 2019 Background: In 2006 the Institute of Medicine reported that combined mental illness and substance use disorder was the second leading cause of disability and death in women and the highest cause in men.
Sweeney, Rebecca
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Social Functioning of Children and Their Parents: Are They Related? [PDF]
, 2010 This study examined whether parents' social support was related to their children's peer acceptance and likability. The moderating role of the parent's and the child's gender was also examined.
Wetzel, Megan
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Intertangled stochastic motifs in networks of excitatory-inhibitory units [PDF]
, 2017 We have benefited from discussions with A. Politi.
Fanelli, Duccio +3 more
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source