Results 41 to 50 of about 2,675,624 (254)

Do peers increase older adults\u27 participation in strength training? Pilot randomized trial [PDF]

open access: yes, 2020
Fewer than 20% of older adults participate in strength training (ST). Barriers to ST participation include not knowing where to go or not having someone to go with.
Burton, Elissa   +4 more
core   +1 more source

Stay Awhile and Listen: User Interactions in a Crowdsourced Platform Offering Emotional Support [PDF]

open access: yes, 2015
Internet and online-based social systems are rising as the dominant mode of communication in society. However, the public or semi-private environment under which most online communications operate under do not make them suitable channels for speaking ...
Calzarossa, Maria-Carla   +5 more
core   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Mammalian Brain As a Network of Networks [PDF]

open access: yes, 2016
Acknowledgements AZ, SG and AL acknowledge support from the Russian Science Foundation (16-12-00077). Authors thank T. Kuznetsova for Fig.
Gordleeva, Susanna   +6 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A method and tool to support the analysis and enhance the understanding of peer-­to-­peer learning experiences [PDF]

open access: yes, 2010
In this paper we look at how a web-based social software can be used to make qualitative data analysis of online peer-to-peer learning experiences. Specifically, we propose to use Cohere, a web-based social sense-making tool, to observe, track, annotate ...
Alevizou, Panagiota, De Liddo, Anna
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Generation of a train of ultrashort pulses using periodic waves in tapered photonic crystal fibres [PDF]

open access: yes, 2016
Funding This work was supported by the Ministry of Education , Nigeria for financial support through the TETFUND scholarship 55 scheme; CSIR [grant number 03(1264)/12/EMR-II].Peer ...
Atubaa, S. O.   +5 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Understanding the role of bystanders and peer support in school bullying [PDF]

open access: yes, 2014
Research into school bullying has traditionally focussed on the actual protagonists – the perpetrators and the targets. Consequently, we know a great deal about the psychological characteristics of bullies and victims and the consequences of bullying ...
Cowie, Helen
core   +1 more source

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