Results 161 to 170 of about 152,756 (308)

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

A Comparative Educational Intervention Study of Peer Teaching and Flipped Classroom Models in Pediatric Intensive Care Rotation. [PDF]

Adv Med Educ Pract
Wu S, Ma J, Zhou L, Huang S, Dong X, Li Y, Huang J, Bai Z.   +7 more
europepmc   +1 more source

The value of near-peer teaching in the medical curriculum: a medical student's perspective

, 2018
Ishar Alexander Kalsi GKT School of Medical Education, Faculty of Life Sciences and Medicine, King’s College London, London, UKIt is with both interest and sympathy that I read the research letter published by Sonagara et al1 about the numerous ...
Kalsi IA
core  

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Enhancing musculoskeletal examination skills through near-peer teaching: student outcomes and perspectives. [PDF]

BMC Med Educ
Qian K, Malau-Aduli B, Sundaraj K.
europepmc   +1 more source

Impact of near-peer teaching on medical English learning motivation among medical students and residents. [PDF]

J Gen Fam Med, 2023
Hoshina Y, Limeisa, Takaiso H, Maki H, Yoshino T, Shikino K.   +5 more
europepmc   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Prepare medical graduates for residency through near-peer teaching: addressing reciprocal determinants. [PDF]

Ann Med
Chien L, Chen TY, Peng CH, Ho H, Liu CW, Liao PH, Kao YH, Yu TC, Lee CY, Chiu YC, Yang CW, Ho CM.   +11 more
europepmc   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source

Near-peer teaching of laparoscopic skills among medical students: a randomised feasibility study. [PDF]

BMC Med Educ
Ho MP, Heskin L, Dablouk L, Richa Y, Nolan J, Brien AO, Abrar S, Hennessey D.   +7 more
europepmc   +1 more source