Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
AI-enabled sports-system peer-to-peer energy exchange network for remote areas in the digital economy. [PDF]
HeliyonLu Y, Hao N, Li X, Alshahrani MY.
europepmc +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Peer-to-peer training among health care professionals working in dialysis clinics: an education approach from the GoodRENal project. [PDF]
J NephrolAvesani CM +7 more
europepmc +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Improving HPV vaccine acceptance through peer-to-peer education among adolescent girls in the urban poor settings of Kisenyi, Kampala, Uganda. [PDF]
PLOS Glob Public HealthTuhebwe D +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
A peer-to-peer infection prevention and control programme in neglected settings: The case of home care and nursing homes in North Italy. [PDF]
J Infect PrevRonco M +3 more
europepmc +1 more source
Leveraging web-services and peer-to-peer networks. [PDF]
Kramer, B.J., Papazoglou, M., Yang, J.
core +1 more source