Results 81 to 90 of about 88,216,106 (291)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A discussion on the ethical issues in peer-to-peer network monitoring [PDF]

open access: yes, 2012
Peer-to-peer networks have gained a significant amount of popularity since their inception, being used in a wide variety of contexts; both legal and illegal.
Sabooniha, N.   +4 more
core  

Interpersonal skills as a Peer Mentor

open access: yes
As a Peer Mentor, your ability to build strong relationships, foster trust, and communicate effectively is ...
Peer Mentoring team
core   +1 more source

A review of peer-to-peer transaction loss and blockchain: challenges and drivers in the roadmap to a low-carbon future

open access: yesFrontiers in Energy Research
Adapting to horizontal market structures faces several drivers and challenges in the context of sustainable energy transition. The inherently decentralized nature qualifies blockchain technology as the major technical driver in the transition to peer-to ...
Maya P, P. Abdul Salam
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Sharing without laws: an exploration of social practices and ad hoc labeling standards in online movie piracy

open access: yesInternet Policy Review, 2016
This paper discusses self-labelling standards as sharing mediators in pirated versions of movies available online. Piracy has existed since the beginning of the film industry, challenging established rules and regulations.
Roberto Tietzmann, Liana Gross Furini
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Peer development as an alternative to peer observation: a tool to enhance professional development [PDF]

open access: yes, 2010
Many Higher Education institutions worldwide require that all academic staff undergo a peer observation of teaching each academic year. Within one department in a university in the South of England, questions have arisen about the value and purpose of ...
Brown, Hazel   +5 more
core   +1 more source

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