Results 91 to 100 of about 18,881 (295)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Pathways between childhood victimization and psychosis-like symptoms in the ALSPAC Birth Cohort [PDF]

, 2013
Background: Several large population-based studies have demonstrated associations between adverse childhood experiences and later development of psychotic symptoms.
Lewis, G., Maughan, B., Fisher, H. L., Lewis, Glyn, Fisher, Helen L; id_orcid, Schreier, Andrea, Lewis, Glyn H, Maughan, Barbara, Maughan, Barbara; id_orcid, Munafo, Marcus R., Wolke, D., Wolke, Dieter, Fisher, H., Zammit, Stanley, Munafò, Marcus R, Munafo, M. R., Schreier, A.   +16 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Trajectories of Peer Victimization: The Role of Multiple Relationships [PDF]

, 2010
This study examined early elementary school children's trajectories of peer victimization with a sample of 218 boys and girls. Peer victimization was assessed (via peer report) in kindergarten and first, second, and fifth grades.
Reavis, Rachael Dianna, Calkins, Susan D., NC DOCKS at The University of North Carolina at Greensboro, Keane, Susan P.   +3 more
core   +2 more sources

Dating violence (DV): a systematic meta-analysis review

Anales de Psicologia, 2020
This study summarizes the results of meta-analyses about risk and protective factors related to dating violence (DV). Fifteen studies were included from 1997 to 2018, N = 1784018. The results were classified according to ecological theory.
Marcela Gracia-Leiva, Alicia Puente-Martínez, Silvia Ubillos-Landa, Darío Páez-Rovira   +3 more
doaj   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Cognitive appraisals, emotional reactions, and their associations with three forms of peer-victimization

, 2012
Victimized students’ cognitive appraisals (perceived threat, control) are related to emotional reactions. Furthermore, psychosocial wellbeing is differentially associated with form of victimization (direct vs.
Hunter, Simon C.; id_orcid, Anderson, Shayron, Hunter, Simon C.   +2 more
core  

"What people tell you gets to you". Body satisfaction and peer victimization in early adolescence.

, 2009
Satisfaction with one’s appearance and peer relationships, respectively, are salient components of adolescents’ everyday lives. Difficulties in either of these domains may be detrimental to individuals’ psychological well-being.
Lunde, Carolina
core   +1 more source

Peer Victimization and Dysfunctional Reward Processing: ERP and Behavioral Responses to Social and Monetary Rewards

Frontiers in Behavioral Neuroscience, 2019
Peer victimization (or bullying) is a known risk factor for depression, especially among youth. However, the mechanisms connecting victimization experience to depression symptoms remains unknown.
Brent I. Rappaport, Laura Hennefield, Autumn Kujawa, Kodi B. Arfer, Danielle Kelly, Emily S. Kappenman, Joan L. Luby, Deanna M. Barch, Deanna M. Barch, Deanna M. Barch   +9 more
doaj   +1 more source