Results 191 to 200 of about 18,881 (295)

Peer victimization and peer sexual harassment across early adolescence: Branches from the same tree or free-standing constructs? [PDF]

J Res Adolesc
Gattario KH, Valik A, Lunde C, Skoog T, Jaf D.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Functional organization of the allostatic interoceptive network in adolescence: Links to peer victimization and prospective depressive symptoms. [PDF]

Dev Cogn Neurosci
Frye NG, Nugiel T, Alvarez GM, Prinstein MJ, Cohen JR, Telzer EH, Lindquist KA.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Gender differences in the relationship between peer victimization and non-suicidal self-injury in adolescents with depressive disorders. [PDF]

Front Psychol
Yin A, Liu S, Wang C, Wang Y, Qiao D, Zhou Y.   +5 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Peer victimization in adolescence alters gene expression and cytokine profiles during transition to adulthood. [PDF]

Brain Behav Immun Health
Heumann J, Cole SW, Eisner M, Ribeaud D, Grünblatt E, Shanahan MJ.   +5 more
europepmc   +2 more sources

Peer Victimization in Childhood and Timing of Substance Use Initiation: Evidence from a Twin Study. [PDF]

Behav Genet
Yu LH, Marceau K, Knopik VS, Baker L.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Parenting and Peer Victimization in the Development of Callous-Unemotional Behaviors: Moderation by Irritability and Basal Cortisol. [PDF]

Res Child Adolesc Psychopathol
Perhamus GR, Ostrov JM, Murray-Close D.
europepmc   +1 more source