Results 51 to 60 of about 2,402 (200)

Harmine Derivatives as Anticancer Agents Endowed With Potent and Selective Antileukemia Activity: Synthesis, Biological Evaluation, Proapoptotic and Genotoxic Activity

Archiv der Pharmazie, Volume 359, Issue 2, February 2026.
We identified a novel N9‐substituted harmine analog, compound 6, that selectively suppresses leukemic cell growth, triggers DNA damage, and activates apoptosis while sparing healthy fibroblasts. This discovery highlights N9‐modified β‐carbolines as a powerful new class of selective antileukemic agents, bridging natural product chemistry with next ...
Abdul Aziz Timbilla, Filip Pidany, Eliska Kohelova, Jana Kroustkova, Karel Kralovec, Jan Rataj, Martina Ceckova, Negar Maafi, Víctor Lopez, Cristina Moliner Langa, Stefan Kosturko, Jaroslav Jenco, Darina Muthna, Darja Koutova, Martina Rezacova, Lucie Cahlikova, Jakub Chlebek, Radim Havelek   +17 more
wiley   +1 more source

Allelopathy as a Strategy for Biological Invasion: Calotropis procera and Its Impact on Plant Succession

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Stages of the study on the allelopathic potential of Calotropis procera (Aiton) W. T. Aiton. The image shows the collection of plant material, the decomposition of organic matter, the identification of bioactive compounds, and the effects on the germination of Handroanthus impetiginosus (Mart. ex DC.) Mattos.
Bruno Melo de Alcântara, Paulo Henrique Calixto Santana, Felipe Rufino dos Santos, José Weverton Almeida‐Bezerra, José Galberto Martins da Costa, Delmira da Costa Silva, Cláudia Maria Furlan, Maria Arlene Pessoa da Silva   +7 more
wiley   +1 more source

Influence of altitude on eco-phytochemical parameters of Peganum harmala, Sophora alopecuriodes and Ziziphora clinopodioides Lam in rangelands of northern Iran

Journal of Agrometeorology, 2019
Northern Iran especially Alborz Mountain range is one of the most important floristic regions of Iran, which has high medicinal plant biodiversity. Research areas were located between the northern part of the Alborz Mountains range and south of the ...
M.R. KHATAMI MOGHADDAM, H. FALLAH, Y. NIKNEJAD, S. DASTAN   +3 more
doaj   +1 more source

Cotyledon Numbers of Two Peganum Species (Peganaceae) in Mongolia [PDF]

Mongolian Journal of Biological Sciences, 2011
Most seedlings of Peganum harmala and P. nigellastrum have two cotyledons, but up to 10% of all seedlings of P. harmala have to three cotyledons, and up to 1.7% has four cotyledons. Up to 5.4% on P.
Narantsetseg Amartuvshin
doaj   +1 more source

Subacute Toxicity Study of Total Alkaloids of Seeds of Peganum harmala in Female Rat [PDF]

, 2014
The effects of subacute administration of total alkaloids of seeds Peganum harmala were studied in female Albino-Wistar rats. After intraperitoneal administration of dose 50 mg/kg for 10 days and 40 mg/kg for 7 days of total alkaloids to the seeds of ...
Mahdeb Nadia, Bouzidi Abdelouahab, Daamouche Z. El Youm, Bettihi Sara, Ghadjati Nadhra   +4 more
core   +1 more source

Ecological Effects of Solanum rostratum Invasion on the Diversity and Functional Traits of Native Plant Communities

Ecology and Evolution, Volume 16, Issue 1, January 2026.
The invasion of Solanum rostratum exerts stage‐dependent effects on native plant communities. The study found that at low invasion levels, it temporarily enhances native plant diversity and community stability through resource complementarity; whereas at high invasion levels, it shifts to strong competitive inhibition, leading to a sharp decline in ...
Lijun Hu, Lamei Jiang, Juan Qiu, Amanula Yimingniyazi   +3 more
wiley   +1 more source

Determination of Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MAC) of seed methanolic extract of Peganumharmala L. against Gram negative bacteria

Kufa Journal for Veterinary Medical Sciences, 2018
 Peganum harmala L. (Zygophyllaceae) used in traditional medicine of Iraq and itis one of the most famous medicinal plants. The most bacteria pathogen is resistance for synthesis antibiotic drugs resulting from abuse uses of the patient or produce ...
Saadia Saleh Mehdy Al-zeiny
doaj   +1 more source

Biological activities of Peganum harmala leaves

, 2015
Ethyl acetate, chloroform, butanol and methanol extracts of the leaves of Peganum harmala were tested for antibacterial, antioxidant and antiviral activities.
Laurent, Gutman, Mighri, Zine, Maha, Mastouri, Mata, Matieu, Mahjoub, Aouni, Hayet, Edziri   +5 more
core   +1 more source

Edible Seeds in the Fight Against Hypertension: A Review of In Vitro, In Vivo, and Clinical Evidences With a Mechanistic Insight of Bioactive Compounds

Food Frontiers, Volume 7, Issue 1, January 2026.
The presented review provides the potential antihypertensive benefits of traditionally employed edible seeds, presenting new perspectives and avenues for future research. ABSTRACT Hypertension, often referred to as a silent killer, is responsible for 7.5 million deaths, representing approximately 12.8% of all global mortality.
Jinmin Shi, Mohamad Fawzi Mahomoodally, Ahmed Abduljalal Abduljabbar, Ruttun Bushra Umme Zainab, Katharigatta N. Venugopala, Gokhan Zengin, Sakina Yagi, Meng‐Yao Li, Xuebo Hu   +8 more
wiley   +1 more source

Evaluation of genetic diversity in wild populations of Peganum harmala L., a medicinal plant

Journal of Genetic Engineering and Biotechnology, 2018
Peganum harmala L. is a perennial herbaceous plant and can be a future drug due to its wide medicinal purposes. Despite its economic importance, the molecular genetics of P. harmal have not yet been studied in detail. Genetic diversity of 12 P.
Ranya EL-Bakatoushi, Dalia Gamil Aseel Ahmed   +1 more
doaj   +1 more source