Results 11 to 20 of about 20,060 (180)

Successful treatment of hairy cell leukaemia with pegylated interferon-alpha-2A [PDF]

open access: yesPathology and Oncology Research
IntroductionHairy cell leukemia (HCL) is an indolent B-cell lymphoproliferative disease. Interferon-alpha (IFN-alpha) was the first successfully used drug in HCL; its favourable effect has been known since the early 1980s.
Kata Ferenczi   +6 more
doaj   +2 more sources

Management of common autoimmune diseases in patients with myeloproliferative neoplasms treated with pegylated interferon alfa—case report, review of the literature and multidisciplinary clinical practice recommendations [PDF]

open access: yesTherapeutic Advances in Hematology
Pegylated interferons alfa are increasingly used in patients with myeloproliferative neoplasms (MPN) due to their potential disease-modifying effect. Ropeginterferon alfa-2b has been approved for patients with polycythemia vera (PV) with no symptomatic ...
Axel Rüfer   +7 more
doaj   +2 more sources

Pegylated interferon: the who, why, and how. [PDF]

open access: yesHematology Am Soc Hematol Educ Program
Abstract Interferon alpha (IFN-α) is a fascinating molecule with many biological properties yet to be fully understood. Among these properties, several have demonstrated usefulness for targeting malignant cells, including hematopoietic cells from patients with myeloproliferative neoplasms.
Kiladjian JJ.
europepmc   +3 more sources

Effect of Pegylated Interferon on Non-Responders and Relapsers with Interferon

open access: yesSultan Qaboos University Medical Journal, 2002
Objectives: To assess whether a combination of pegylated interferon (interferon conjugated with polyethylene glycol) and ribavirin can improve the response rate in patients with chronic hepatitis C who either did not respond to (Non-responders), or had ...
Hisham O. Akbar, Mahmoud S. Al Ahwal
doaj   +3 more sources

Results of interferon-based treatments in Alaska Native and American Indian population with chronic hepatitis C [PDF]

open access: yesInternational Journal of Circumpolar Health, 2016
Background: There have been few reports of hepatitis C virus (HCV) treatment results with interferon-based regimens in indigenous populations. Objective: To determine interferon-based treatment outcome among Alaska Native and American Indian (AN/AI ...
Stephen E. Livingston   +8 more
doaj   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

open access: yesHepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah   +2 more
wiley   +1 more source

Importance of adherence for efficacy of hepatitis C combined therapy [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2013
Introduction. Dual antiviral therapy with pegylated interferon alfa-2a and ribavirin leads do sustained elimination of hepatitis C virus infection in over 50% patients with genotypes 1 and 4 and in over 80% with genotypes 2 and 3.
Nožić Darko   +5 more
doaj   +1 more source

Early Treatment with Pegylated Interferon Lambda for Covid-19. [PDF]

open access: yesN Engl J Med, 2023
Reis G   +41 more
europepmc   +2 more sources

Screening for hepatitis D and PEG-Interferon over Tenofovir enhance general hepatitis control efforts in Brazil. [PDF]

open access: yesPLoS ONE, 2018
BACKGROUND:Hepatitis D virus (HDV), which requires the presence of hepatitis B virus (HBV), is a deadly yet neglected disease that rapidly leads to liver cancer and disease-induced mortality.
Ashish Goyal, Ethan Obie Romero-Severson
doaj   +1 more source

Interferon-λ treatment accelerates SARS-CoV-2 clearance despite age-related delays in the induction of T cell immunity

open access: yesNature Communications, 2022
The interferon response is a critical component response to SARS-CoV-2 infection and prior studies have established a role for the administration of PEGylated interferon-lambda1 and its impact on viral clearance.
Deanna M. Santer   +8 more
doaj   +1 more source

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