Results 71 to 80 of about 182,433 (270)
Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy
Angewandte Chemie International Edition, EarlyView.Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean +3 more
wiley +1 more source
, 2014 The baseline characteristics and treatment outcome between the patients treated with Pegylated interferon-Alfa-2a and Pegylated interferon-Alfa-2b.
Tsung-Hsing Hung (579080) +8 more
core +1 more source
Boğaziçi Tıp Dergisi, 2020 INTRODUCTION[|]Hepatitis B and hepatitis C infections are the major causes of death due to chronic liver disease. Treatment is very important in reducing long-term cirrhosis and hepatocellular carcinoma. In this study, we aimed to determine the real-life
Servet Öztürk, Nesrin Turker
doaj +1 more source
Navigating adverse immunostimulation: A practical guide for clinical researchers
British Journal of Clinical Pharmacology, EarlyView.Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort +3 more
wiley +1 more source
Brazilian Journal of Biology, 2021 Although increased response rates concomitant in hepatitis C virus but relapse after treatment is threatened. Therefore, it is terrible requirement to evaluate the response of Pegylated interferon and direct acting antivirals in Punjab Pakistan.
M. N. Raza +7 more
doaj +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
BMEMat, EarlyView.Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
, 2006 Background/Aim Although 48-week therapy with pegylated-interferons has been shown to be effective for the treatment of chronichepatitis B virus (HBV) infection, the efficacy of a shorter durationof therapy with pegylated interferons is unknown.Method We ...
Lo, CM +11 more
core +1 more source
PK/PD modelling of comb-shaped PEGylated salmon calcitonin conjugates of differing molecular weights [PDF]
, 2010 Salmon calcitonin (sCT) was conjugated via cysteine-1 to novel comb-shaped end-functionalised (poly(PEG) methyl ether methacrylate) (sCT-P) polymers, to yield conjugates of total molecular weights (MW) inclusive of sCT: 6.5, 9.5, 23 and 40 kDa.
Jesús M. Frías +15 more
core +1 more source
Treatment of Autoimmune Haemolytic Anaemia with Hepatitis C Virus-A Real Challenge
Sri Lankan Journal of Infectious Diseases, 2016 Hepatitis C virus (HCV) infection is a potentially curable disease. The first line of treatment is pegylated interferon and ribavirin, both of which cause haemolysis. HCV itself causes autoimmune haemolytic anaemia (AIHA).
A Basu +4 more
doaj +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source