Results 101 to 110 of about 10,402 (207)

Phase Ii Trial of Carboplatin and Distearoylphosphatidylcholine Pegylated Liposomal Doxorubicin (Lipo-Dox) in Recurrent Platinum-Sensitive Ovarian Cancer Following Front-Line Therapy with Paclitaxel and Platinum

, 2011
OBJECTIVE: To evaluate the effectiveness and toxicity of distearoylphosphatidylcholine pegylated liposomal doxorubicin (DPLD) combined with carboplatin for the treatment of platinum-sensitive, paclitaxel-pretreated, recurrent, epithelial ovarian cancer ...
HSIAO, SHENG-MOU;CHEN, CHI-AN;LIN, HO-HSIUNG;HSIEH, CHANG-YAO;WEI, LIN-HUNG, 蕭聖謀;陳祈安;林鶴雄;謝長堯;魏凌鴻   +1 more
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Pegylated liposomal doxorubicin-related palmar-plantar erythrodysesthesia ('hand-foot' syndrome)

, 2007
Palmar-plantar erythrodysesthesia (PPE), also called hand-foot syndrome or hand-to-foot syndrome, is a distinctive and relatively frequent dermatologic toxic reaction associated with certain chemotherapeutic agents. Pegylated liposomal doxorubicin (PLD),
Fagotti A., Scambia G., Lorusso D.
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PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin

, 2013
Improved delivery of chemotherapeutic drugs to the lymphatic system has the potential to augment outcomes for cancer therapy by enhancing activity against lymph node metastases.
Bulitta, Juergen B., Ryan, Gemma M., McIntosh, Michelle P., Owen, David J., Porter, Christopher J. H., Kaminskas, Lisa M.   +5 more
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Treatment of inoperable hepatocellular carcinoma with pegylated liposomal doxorubicin (PLD): Results of a phase II study

, 2005
Monthly intravenous pegylated liposomal doxorubicin (PLD) 50 mg m -2, although well tolerated, showed almost no activity in this phase II study of 16 patients with advanced hepatocellular carcinoma with a response rate of 0%, stable disease 19%, median ...
S M Lee, Scarffe, J. H., Ranson, M., J Beech, Sherlock, D. J., J W Valle, A Dangoor, Dangoor, A., Beech, J., Swindell, R., D J Sherlock, Valle, J. W., J H Scarffe, R Swindell, Lee, S. M., M Ranson   +15 more
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Reactive Oxygen Species-Mediated Inflammation and Apoptosis in Hand-Foot Syndrome Induced by PEGylated Liposomal Doxorubicin

International Journal of Nanomedicine, 2021
Xiaolin Hu,1,2 Mengmeng Dong,2 Xiao Liang,2 Ziling Liu,1 Quanshun Li2 1Cancer Center, The First Hospital of Jilin University, Changchun 130012, People’s Republic of China; 2Key Laboratory for Molecular Enzymology and Engineering of Ministry of ...
Hu X, Dong M, Liang X, Liu Z, Li Q
doaj  

Phase II Study of Bortezomib and Pegylated Liposomal Doxorubicin in the Treatment of Metastatic Breast Cancer

, 2010
Based on preclinical studies and a phase I trial of the combination of bortezomib and pegylated liposomal doxorubicin (PLD), which both showed activity in breast cancer, we conducted a phase II study of this regimen in patients with metastatic breast ...
Charles Perou, Anastasia Ivanova, Bernard, Philip S., Stijleman, Inge J., Robert Z. Orlowski, Orlowski, Robert Z., Carey, Lisa A., Perou, Charles, Lisa A. Carey, Philip S. Bernard, Dees, E. Claire, Inge J. Stijleman, Collichio, Frances A., Ivanova, Anastasia, Frances A. Collichio, Irvin Jr., William J., William J. Irvin, Chiu, Wing Keung, Wing-Keung Chiu, E. Claire Dees   +19 more
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Chemotherapy with pegylated liposomal doxorubicin and cisplatin in recurrent platinum-sensitive epithelial ovarian cancer

, 2008
Background. Pegylated liposomal doxorubicin (PLD) is the only nonplatinum agent to significantly improve survival in patients with platinum-sensitive recurrent ovarian cancer.
Tas, Faruk, Aydiner, Adnan, Topuz, Erkan, Derin, Duygu, Guney, Nese   +4 more
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A case of advanced Hodgkin lymphoma with breast involvement treated with a combination of gemcitabine and pegylated liposomal doxorubicin.

, 2005
Gemcitabine in combination with pegylated liposomal doxorubicin has been recognized as an effective treatment in patients with refractory solid tumors.
FEGGI, Luciano, PANAREO, Stefano, CHIERICHETTI F., FRAULINI, Chiara, MAURO, Endri, RIGOLIN, Gian Matteo, CAVAZZINI, Luigi, CASTOLDI, Gianluigi, BISSOLI S.   +8 more
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Incidence of Cardiotoxicity Associated with the Use of Pegylated Liposomal Doxorubicin in Gynecologic Malignancies

Biomedical Sciences and Clinical Medicine
Objective This study aims to evaluate the incidence of cardiotoxicity in patients with gynecologic cancer undergoing pegylated liposomal doxorubicin (PLD) treatment and to identify risk factors for developing changes in the left ventricular ...
Teerit Angkatavanich, Supreechaya Phansenee, Kristsanamon Rittiluechai, Suttida Intharaburan   +3 more
doaj   +1 more source

A phase II study of combination chemotherapy in early relapsed epithelial ovarian cancer using gemcitabine and pegylated liposomal doxorubicin

, 2010
Treatment of epithelial ovarian cancer patients relapsing with a short treatment-free interval (TFI) after prior chemotherapy is unsatisfactory. This phase II trial evaluated the activity and feasibility of pegylated liposomal doxorubicin (PLD) plus ...
Bente Lund, Nina Keldsen, Mirza, Mansoor Raza, Mansoor Raza Mirza, Keldsen, Nina, Jacob Christian Lindegaard, Kamma Bertelsen, Christensen, René dePont, René dePont Christensen, Lund, Bente, Lindegaard, Jacob Christian, Bertelsen, Kamma, Mellemgaard, Anders, Anders Mellemgaard   +13 more
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