Results 221 to 230 of about 373,225 (307)

Molecular Design of Polymer Dielectrics With Local State Traps for High-Temperature Energy Storage. [PDF]

Small
Zhao W, Huang W, Han J, Hu D, Li T, Zhu L, Jung YC, Wen Y, Zha JW.   +8 more
europepmc   +1 more source

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

Advanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng, Jianhua Wang, Tao Zhang, Xiaofan Fan, Jinxiu Guo, Shiyuan Zhao, Wenxue Sun, Pei Jiang   +7 more
wiley   +1 more source

A Mechanistic Dissection of Multifaceted Complement Attack in Age‐Related Macular Degeneration Reveals the Superiority of C3 Inhibition

Advanced Science, EarlyView.
Complement‐mediated RPE degeneration extends beyond terminal MAC injury. A four‐hit mechanism emerges in which C3a and C5a disrupt mitochondrial function, while C3b and MAC compromise the phagolysosomal system. Upstream C3 inhibition suppresses this full spectrum of pathogenic effectors, providing broader cellular protection than C5 blockade.
Zhidong Chen, Mingshuang Wang, Huiqin Liu, Feng Qian   +3 more
wiley   +1 more source

Correction to "Enzyme-Activated Dual-Locked Probes for Detecting Nitroreductase and Carboxylesterase". [PDF]

Chem Biomed Imaging
Chong X, Luo Z, Liu J, Jiang W, Cen J, Gong Y, Tan L, Pei Z, Jiang G, Zhu Y, Meng WQ.   +10 more
europepmc   +1 more source

Intelligent Polymer Electrolytes for Next‐Generation Zinc‐Based Energy Storage Devices

Advanced Science, EarlyView.
Intelligent polymer electrolytes are organized into a three‐level hierarchy that advances zinc‐based energy storage from passive ion conduction toward active, adaptive, and intelligent operation. Molecular regulation of Zn+ coordination, water activity, desolvation, ion flux, and interfaces underpins adaptive self‐healing, anti‐freezing, adhesion, and ...
Sanath Kumar, Jhansirani Kesavan, Muhammad Asim, Atul Verma, Yen‐Pei Fu   +4 more
wiley   +1 more source

Dynamic Supercooled Crystal–Gels for Ultrafast, Reversible Mechanical Adaptative Materials

Advanced Science, EarlyView.
A dynamic supercooled crystal–gel mimics starfish tissue by storing non‐equilibrium energy in a metastable liquid. A gentle touch triggers templated crystallization, producing a 2596‐fold stiffness increase with negligible volume change. The lattice disintegrates reversibly under humidity or warmth.
Yuesong Lv, Hao Feng, Zhangqin Yang, Jianping Yin, Hanfei Li, Bo Zhou, Yuyang Meng, Yuntong Su, Xinxing Zhang, Xibo Pei   +9 more
wiley   +1 more source

Aminated Wood Aerogel via Tannic Acid/Polyethylenimine Co-Deposition for Enhanced Congo Red Removal. [PDF]

Gels
Li Z, Wang L, Xue X, Yin M, Zhang L, Wang X, Zhou B, Dong Y, Chen X, Mo L, Li C.   +10 more
europepmc   +1 more source

Lactylation of HSC70 Impairs Chaperone‐Mediated Autophagy to Promote Pyrin Inflammasome‐Dependent PANoptosis in Macrophages During Sepsis

Advanced Science, EarlyView.
In sepsis, lactate accumulation drives HSC70 K561 lactylation, which impairs chaperone‐mediated autophagy and blocks CUX1 degradation. Accumulated CUX1 transcriptionally upregulates Pyrin, triggering PANoptosis in macrophages and exacerbating inflammatory storm and organ injury.
Ying Chen, Yan Zhang, Pei Wang, Jiamin Ma, Xinru Zhao, Yi Li, Zhenghao Deng, Xueqing Meng, Jiali Zhu, Liangfang Yao, Jinbao Li   +10 more
wiley   +1 more source

Beta-cyclodextrin-based polymerized nanocarriers for doxorubicin delivery to cancer cells. [PDF]

Nanoscale Adv
Aslam M, Nazir MS, Asghar A, Ahmed A, Anjum H, Ikram F, Jaffer A, Asif A.   +7 more
europepmc   +1 more source