Results 71 to 80 of about 586,078 (308)
Automated image analysis of iron-ore pellet structure using optical microscopy [PDF]
Knowledge about pellet microstructure such as porosity and oxidation degree is essential in improving the pellet macro-behavior such as structural integrity and reduction properties. Manual optical microscopy is commonly used to find such information but
Thurley, Matthew, +5 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Wood-based bioenergy systems developed and managed by Indigenous communities can improve their ability to thrive and grow economically and socially and improve their resource-based decision-making processes.
Nicolas Mansuy +2 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
"New technologies of pellet production and acceleration for fueling and diagnostics purposes in large thermonuclear reactors are proposed. The technologies are intended to apply to the multiple-pellet injection system ""HIPEL"" for Large Helical Device ...
"Viniar, I., Sudo, S."
core
Mathematical model of phase composition diagram of CaO – SiO2 - Fe2O3 - В2О2 system
There is developed a method of the mathematical description of a phase composition diagram of n-component systems in the (n - 1) - dimensional space. There is built a phase composition diagram of the CaO – SiO2 - Fe2O3 - В2О2 system and developed its ...
A. Isagulov +3 more
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Pellet Ablation in Large Helical Device
"In the program of physical studies on the Large Helical Device (LHD) injection of several hydrogen and deuterium pellets is foreseen. Injection of impurity pellets also may be useful for the plasma diagnostics.
"Kuteev, B. V."
core
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source

