Results 41 to 50 of about 58,121 (330)

Stem Cells in Clinical Trials for Pelvic Floor Disorders: a Systematic Literature Review

Reproductive Sciences, 2021
Pelvic floor disorders (PFDs) include a series of conditions that can be poorly tolerated, negatively affecting the quality of life. Current treatment options show unsatisfactory results and new ones are therefore needed.
S. Manodoro, M. Frigerio, M. Barba, S. Bosio, Luigi Antonio de Vitis, A. Marconi   +5 more
semanticscholar   +1 more source

Pathogenesis of dyspareunia associated with pelvic floor dysfunction: A review [PDF]

Гинекология, 2023
Dyspareunia is a condition associated with a wide range of disorders. Pelvic floor dysfunction, manifesting as a myofascial syndrome or pelvic floor muscle hypertonia, may predict dyspareunia in women in different age groups.
Elena S. Silantyeva, Mekan R. Orazov, Marina B. Khamoshina, Evgeniia K. Astafeva   +3 more
doaj   +1 more source

Comparison of 3-Dimensional Pelvic Floor Ultrasonography and Defecography for Assessment of Posterior Pelvic Floor Disorders [PDF]

Annals of Coloproctology, 2020
Purpose The aim of this study was to determine the accuracy of 3-dimensional (3D) pelvic floor ultrasonography and compare it with defecography in assessment of posterior pelvic disorders.
Hong Yoon Jeong, Shi-Jun Yang, Dong Ho Cho, Duk Hoon Park, Jong Kyun Lee   +4 more
doaj   +1 more source

DELIVERY AND PELVIC FLOOR DYSFUNCTION

İstanbul Tıp Fakültesi Dergisi, 2021
Urinary incontinence, anal incontinence, pelvic organ prolapse and sexual dysfunction are included in the definition of pelvic floor dysfunction. Pregnancy and childbirth play a major role in the emergence of pelvic floor dysfunction, which is seen in 41%
Nezihe Kızılkaya Beji, Elif Zahide Çelebi, Nilgün Avcı   +2 more
doaj   +1 more source

CDK12-Mediated Phosphorylation of FOXA1 Promotes Prostate Cancer Progression via the MDM2–p53 Axis

Research
Prostate cancer (PCa) progression is driven by intricate molecular mechanisms involving dysregulated signaling networks and posttranslational modifications of key regulatory proteins.
Binyuan Yan, Mengjun Huang, Jinxiang Wang, Hanqi Lei, Tongyu Tong, Bin Xu, Fei Cao, Qiliang Teng, Jinsheng Huang, Yupeng Guan, Wenjun Mao, Haojie Huang, Jun Pang   +12 more
doaj   +1 more source

Pelvic floor dysfunction: prevalence and associated factors

BMC Public Health, 2023
Background Pelvic floor dysfunction in women encompasses a wide range of clinical disorders: urinary incontinence, pelvic organ prolapse, fecal incontinence, and pelvic-perineal region pain syndrome.
Rocío Adriana Peinado-Molina, Antonio Hernández-Martínez, Sergio Martínez-Vázquez, Julián Rodríguez-Almagro, Juan Miguel Martínez-Galiano   +4 more
doaj   +1 more source

One in five women suffer from pelvic floor disorders in Kersa district Eastern Ethiopia: a community-based study

BMC Women's Health, 2018
Background Hundreds of millions of women suffer from pelvic floor disorders globally, often in silence. Women in developing countries do not disclose their problems due to associated social stigma or lack of access to services.
Merga Dheresa, Alemayehu Worku, Lemessa Oljira, Bizatu Mengiste, Nega Assefa, Yemane Berhane   +5 more
doaj   +1 more source

Impact of Poly(Ester Amide) Structure on Properties and Drug Delivery for Prostate Cancer Therapy

BME Frontiers, 2023
Objective: We aim to develop a polymer library consisting of phenylalanine-based poly(ester amide)s (Phe-PEAs) for cancer therapy and investigate the structure–property relationship of these polymers to understand their impact on the drug delivery ...
Junfu Zhang, Liying Wang, Mengting Ding, Xinru You, Jun Wu, Jun Pang   +5 more
doaj   +1 more source

Clinical Use of S53P4 Bioactive Glass in the Treatment of Bone Defects and Infected Bone: A Systematic Review of the Quality of Clinical Outcomes and A Grade Assessment

Advanced Healthcare Materials, EarlyView.
Bioactive glass (BAG) S53P4 is a synthetic bone substitute. Clinically it has been used in the treatment of benign bone tumor surgery, in spine surgery, in trauma surgery, in frontal sinus surgery, in diabetic foot osteomyelitis surgery, in mastoid surgery, in oral and maxillofacial surgery in more than 4000 patients, with excellent clinical long‐term ...
Sebastian CE Lindfors, Chris JJ Arts, Nina C Lindfors   +2 more
wiley   +1 more source

Frontier knowledge and future directions of programmed cell death in clear cell renal cell carcinoma

Cell Death Discovery
Clear cell renal cell carcinoma (ccRCC) is one of the most common renal malignancies of the urinary system. Patient outcomes are relatively poor due to the lack of early diagnostic markers and resistance to existing treatment options.
Cao Fei, Xu Zhen, Zhang Shiqiang, Pang Jun   +3 more
doaj   +1 more source