Results 201 to 210 of about 26,153 (246)

Relapsing facial pemphigus vegetans associated with chronic intranasal cocaine use. [PDF]

open access: yesJAAD Case Rep
Shin W   +5 more
europepmc   +1 more source

Incidence Trends and Severe in-Hospital Outcomes of Pemphigus Vulgaris: A Nationwide Cohort Study. [PDF]

open access: yesJ Dermatol
Wongjirattikarn R   +8 more
europepmc   +1 more source

Pemphigus

Journal of the European Academy of Dermatology and Venereology, 2008
AbstractPemphigus refers to a group of potentially life‐threatening autoimmune diseases of the skin and mucous membranes, characterized by the formation of blisters and erosions of the skin. An autoimmune process, directed against keratinocyte desmosomal cadherins, interferes with the adhesive function of these molecules. This results in the separation
D, Ioannides   +2 more
openaire   +2 more sources

Pemphigus

The Lancet, 2019
Pemphigus consists of a group of rare and severe autoimmune blistering diseases mediated by pathogenic autoantibodies mainly directed against two desmosomal adhesion proteins, desmoglein (Dsg)1 and Dsg3 (also known as DG1 and DG3), which are present in the skin and surface-close mucosae.
Schmidt, Enno   +2 more
openaire   +4 more sources

Pemphigus

La Presse Médicale, 2010
Pemphigus is a rare autoimmune blistering disorder involving the skin and mucosae. Three types of pemphigus have been described, including pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus. Diagnosis of the type of pemphigus is made by the combination of clinical features, histological and direct immunofluorescence findings, and ...
Hélène, Lapeyre-Liénard, Pascal, Joly
openaire   +2 more sources

Pemphigus

Dermatologic Clinics, 1988
The term pemphigus refers to a group of autoimmune intraepidermal blistering diseases of the skin and mucous membranes. Several clinical variants of pemphigus are recognized. The major histologic feature of all variants is acantholysis, the disruption of normal cell-to-cell adhesion, which leads to intraepidermal blister formation.
openaire   +3 more sources

Pemphigus

Clinical Pharmacology & Therapeutics, 1974
Pemphigus is a disease affecting principally the epidermis and mucous membranes of man. The disease is quite distinctive clinically, histologically, and immunologically. It is of importance to discuss in this Workshop because of two interesting facets: the role played in pathogenesis by circulating autoantibodies and the huge doses of corticosteroids ...
openaire   +2 more sources

Pemphigus Vulgaris and Paraneoplastic Pemphigus

Oral and Maxillofacial Surgery Clinics of North America, 2008
The history, epidemiology, pathophysiology, clinical presentation, diagnostic work-up, histopathology, and treatment of PV and PNP have been presented. These life-threatening, autoimmune, mucocutaneous bullous conditions may be encountered first by oral health providers and, therefore, deserve keen understanding and attention by the oral and ...
Wendell A, Edgin   +2 more
openaire   +2 more sources

Rituximab in Pemphigus

Immunotherapy, 2017
Pemphigus is a severe autoimmune blistering disease mediated by pathogenic anti-desmoglein antibodies leading to an inter keratinocyte disjunction. Rituximab is a monoclonal antibody that binds to the CD-20 antigen of B lymphocytes, which causes B-cell depletion and a subsequent reduction in pathogenic autoantibodies.
Hebert, Vivien, Joly, Pascal
openaire   +2 more sources

Pemphigus: Pemphigus vulgaris and pemphigus foliaceus

1990
The term pemphigus stems from the Greek pemphix (blister) [1] and describes a group of chronic blistering skin diseases in which autoantibodies are directed against the cell surface of keratinocytes, resulting in the loss of cohesion between epidermal cells, through a process called acantholysis. Pemphigus is divided into pemphigus vulgaris (PV) with a
Stephan Müller, John R. Stanley
openaire   +1 more source

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