Results 1 to 10 of about 7,208 (133)

Ultrastructural skin alterations of healthy subjects with anti-desmoglein 1 antibodies in endemic areas to pemphigus foliaceus: A case series [PDF]

Journal of Translational Autoimmunity, 2023
Background: Endemic pemphigus foliaceus and endemic pemphigus vulgaris are autoimmune dermatologic disorders endemic to the Peruvian Amazon. Objective: To determine the ultrastructural skin alterations of three healthy subjects with anti DSG-1 antibodies
Willy Ramos, Nancy Rojas, Alex G. Ortega-Loayza, Mercedes Tello, Gerardo Jiménez, Nicolás Cuba-Cáceres, Gerardo Ronceros, Jhony A. De La Cruz-Vargas, Víctor Juan Vera-Ponce, Nadia Guerrero, Ericson L. Gutierrez   +10 more
doaj   +2 more sources

Endocytosis of IgG, Desmoglein 1, and Plakoglobin in Pemphigus Foliaceus Patient Skin [PDF]

Frontiers in Immunology, 2019
Pemphigus foliaceus (PF) is one of the two main forms of pemphigus and is characterized by circulating IgG to the desmosomal cadherin desmoglein 1 (DSG1) and by subcorneal blistering of the skin.
Dyah A. M. Oktarina, Dyah A. M. Oktarina, Ena Sokol, Duco Kramer, Marcel F. Jonkman, Hendri H. Pas   +5 more
doaj   +2 more sources

IgA pemphigus showing IgA antibodies to desmoglein 1 and 3 [PDF]

Dermatology Practical & Conceptual, 2016
Background: IgA pemphigus is a rare autoimmune vesiculo-pustular skin disease. Only approximately 70 cases have been reported to date. We report a case of IgA pemphigus with IgA antibodies to desmoglein 1 (Dsg1) and desmoglein 3 (Dsg3).
Salama Hegazy, Sana Bouchouicha, Aida Khaled, Lilia Laadher, Maryem Kallel Sellami, Faten Zeglaoui   +5 more
doaj   +2 more sources

Hereditary epidermolytic palmoplantar keratosis due to a novel desmoglein‐1 mutation: A case report [PDF]

Clinical Case Reports
Key Clinical Message Keratosis palmoplantaris striata type I (SPPK‐I) is a rare autosomal‐dominant type of hereditary epidermolytic palmoplantar keratoderma, which can be caused by mutations in desmoglein‐1 (DSG‐1).
Kevin Koschitzki, Bernadett Kurz, Julia Schreml, Judith Fischer, Alrun Hotz, Christoph M. Hammers, Mark Berneburg, Dennis Niebel, Stephan Schreml   +8 more
doaj   +2 more sources

Non-COVID-19 Vaccinations and the Induction of Autoantibodies in Pemphigus Diseases: A Review of the Speculative Issue and Our Clinical-Laboratory Experience [PDF]

Antibodies
Background: Pemphigus diseases are rare autoimmune blistering disorders mediated by pathogenic autoantibodies directed mainly against desmoglein 1 and desmoglein 3.
Maksymilian Markwitz, Natalia Welc, Klementyna Kępińska, Monika Bowszyc-Dmochowska, Marian Dmochowski   +4 more
doaj   +2 more sources

Desmoglein-1 Deficiency Mimicking Omenn Syndrome

Indian Journal of Dermatology
Meltem Comert, Tugba Guler, Ayca Ceylan, İlknur Kulhas Celik, Pinar Karabagli, Tulin Cora, Hasibe Artac   +6 more
doaj   +2 more sources

Desmoglein autoantibodies and disease severity in pemphigus patients – correlations and discrepancies [PDF]

Folia Medica, 2023
Aim: To assess the correlation between the levels of anti-desmoglein-1 and anti-desmoglein-3 autoantibodies and disease severity in pemphigus patients.
Zhaneta H. Zhelyazkova, Tsvetana I. Abadjieva, Petya A. Gardjeva, Mariana A. Murdjeva, Tsonka M. Miteva-Katrandzhieva   +4 more
doaj   +3 more sources

Evaluation of desmoglein 1 and desmoglein 3 autoantibodies in oral cancer: A pilot study

Journal of Indian Academy of Oral Medicine and Radiology, 2023
Background: Carcinogenesis is a complex multistep process involving alterations at the cellular level. Alteration in cell-to-cell adhesion of oral epithelium plays an important role in carcinogenesis and metastasis.
Pavan Kumar Yellarthi, Arvind Muthukrishnan, Raghurama Rao Gandikota, Y Sandhya Pavankumar, Divya Uppala   +4 more
doaj   +1 more source

HLA class II antigens in Croatian patients with pemphigus vulgaris and their correlation with anti-desmoglein antibodies

Frontiers in Immunology, 2023
Pemphigus vulgaris (PV) is an acquired autoimmune blistering disease characterized by the production of autoantibodies targeting desmosomal cadherins, primarily desmoglein 1 and desmoglein 3, leading to acantholysis. The etiology of PV is multifactorial,
Ines Lakoš Jukić, Ines Lakoš Jukić, Mislav Mokos, Branka Marinović, Branka Marinović   +4 more
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source