Results 31 to 40 of about 29,699,951 (159)

Involvement of Nail Apparatus in Pemphigus Vulgaris in Ethnic Poles Is Infrequent

open access: yesFrontiers in Medicine, 2018
Pemphigus vulgaris lesions have a tendency to localize around natural body orifices. The aim here was to analyze the involvement of nail apparatus in pemphigus vulgaris.
Pawel Pietkiewicz   +4 more
doaj   +1 more source

Calcium-Dependent Conformation of Desmoglein 1 Is Required for its Cleavage by Exfoliative Toxin [PDF]

open access: yes, 2003
In bullous impetigo, Staphylococcus aureus spreads under the stratum corneum of skin by elaboration of exfoliative toxin, which hydrolyzes only one peptide bond in a highly structured calcium-binding domain of desmoglein 1, resulting in loss of its ...
Stanley, John R.   +5 more
core   +1 more source

Evidence for Dsg3 in regulating Src signaling by competing with it for binding to caveolin-1

open access: yesData in Brief, 2016
This data article contains extended, complementary analysis related to the research articles entitled “Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src” (Tsang et al., 2010) [1] and figures related to the review ...
Hong Wan   +3 more
doaj   +1 more source

Damaged Keratin Filament Network Caused by KRT5 Mutations in Localized Recessive Epidermolysis Bullosa Simplex

open access: yesFrontiers in Genetics, 2021
Epidermolysis bullosa simplex (EBS) is a blistering dermatosis that is mostly caused by dominant mutations in KRT5 and KRT14. In this study, we investigated one patient with localized recessive EBS caused by novel homozygous c.1474T > C mutations in ...
Fuying Chen   +14 more
doaj   +1 more source

In situ image analysis shows decreased protein expression of desmoglein-1 and claudin-1 in the DMPA group.

open access: yes, 2022
Immunofluorescence images of ectocervical tissue sections, and their corresponding digitalized images stained for desmoglein-1 in green (A) and claudin-1 in red (B). All nuclei are stained with DAPI (blue).
Paulo Czarnewski (5820374)   +16 more
core   +1 more source

Distinct impact of IgG subclass on autoantibody pathogenicity in different IgG4-mediated diseases

open access: yeseLife, 2022
IgG4 is the least potent human IgG subclass for the FcγR-mediated antibody effector function. Paradoxically, IgG4 is also the dominant IgG subclass of pathogenic autoantibodies in IgG4-mediated diseases.
Yanxia Bi   +11 more
doaj   +1 more source

Pemphigus Foliaceus and Pemphigus Vulgaris Autoantibodies React with the Extracellular Domain of Desmoglein-1 [PDF]

open access: yes, 1995
Pemphigus foliaceus is associated with an autoimmune response against desmoglein-1; however, the fine specificity of these autoantibodies and the role that they play in pathogenesis have not yet been elucidated.
Emery, Daryl J.   +5 more
core   +1 more source

Factors associated with non-pathogenic antibodies against desmoglein-3 in pemphigus foliaceus [PDF]

open access: yesAnais Brasileiros de Dermatologia
Background Anti-desmoglein (Dsg)1 is produced in pemphigus foliaceus (PF), affecting exclusively the skin. Pemphigus vulgaris (PV) shows the production of anti-Dsg3 in the mucosal form, and anti-Dsg1 and 3 in the mucocutaneous form.
Sebastian Vernal   +5 more
doaj   +1 more source

Genetic Evidence for a Novel Human Desmosomal Cadherin, Desmoglein 4 [PDF]

open access: yes, 2003
Desmosomes are essential adhesion structures in most epithelia that link the intermediate filament network of one cell to its neighbor, thereby forming a strong bond.
Bower, Christopher   +3 more
core   +1 more source

The many faces of Aire in central tolerance

open access: yesFrontiers in Immunology, 2013
Although the role that Autoimmune Regulator (Aire) plays in the induction of central tolerance is well known, the precise cellular and molecular mechanisms are still unclear and debated.
Martti eLaan, Pärt ePeterson
doaj   +1 more source

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