Results 51 to 60 of about 29,699,951 (159)

Antibodies against the Celiac Peptide Recognize Desmoglein 1

, 2013
(A) Sequence homology between the celiac peptide and cell junction proteins. The peptide sequence was compared with known protein sequences using the BLASTP via the NCBI BLAST network service (colons indicate identity and asterisks indicate conservative ...
Giuseppe Tridente (65728), Enrico Valletta (65730), Giovanna Zanoni (65727), Caterina Bason (12871), Antonio Puccetti (12876), Claudio Lunardi (12868), Simona Sivori (65729), Ruggero Beri (12874), Roberto Corrocher (12875), Riccardo Navone (12872), Marzia Dolcino (12869)   +10 more
core   +1 more source

Pemfigus Vulgaris: Laporan Kasus (Pemphigus vulgaris after covid-19 vaccine: association or coincidence?)

JKS (Jurnal Kedokteran Syiah Kuala), 2022
karena produksi autoantibodi terhadap protein desmosomal kulit, yaitu desmoglein (Dsg) 1 dan desmoglein 1 Dsg3. Beberapa faktor termasuk kerentanan genetik, obat-obatan tertentu dan keganasan telah dilaporkan memicu atau memperburuk PV.
Nanda Earlia, Mimi Maulida, Vella Vella, Mikyal Bulqiah, Aqil Yuniawan Tasrif, Aulia Aulia   +5 more
doaj   +1 more source

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid, Peter G. Hains, Velda X. Han, Jingya Yan, Michael Griffiths, Ignatius Pang, Sushil Bandodkar, Phillip J. Robinson, Russell C. Dale   +8 more
wiley   +1 more source

Staphylococcal scalded skin syndrome: loss of desmoglein 1 in patient skin

, 2010
Staphylococcal scalded skin syndrome (SSSS) is a blistering disease of the skin caused by an infection with certain strains of Staphylococcus aureus. In vitro studies have suggested that exfoliative toxins secreted by these bacteria cleave the desmosomal
Aalfs, A. Susanne, Jonkman, Marcel F., Pas, Hendri H., Diercks, Gilles F. H.; id_orcid, Oktarina, D. A. Mira, Diercks, Gilles F. H.   +5 more
core   +1 more source

Implications of normal and disordered remodeling dynamics of corneodesmosomes in stratum corneum

Dermatologica Sinica, 2015
Desmosomes and corneodesmosomes are the most important adhering junctions, providing strength for the epidermal sheet structure made of living keratinocytes and enucleated stratum corneum corneocytes, respectively.
Yasuo Kitajima
doaj   +1 more source

Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model

Frontiers in Medicine, 2022
Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3.
Uta Katharina Radine, Valéria Bumiller-Bini Hoch, Valéria Bumiller-Bini Hoch, Angelica B. Winter Boldt, Detlef Zillikens, Detlef Zillikens, Ralf J. Ludwig, Ralf J. Ludwig, Ralf J. Ludwig, Christoph M. Hammers, Christoph M. Hammers, Christoph M. Hammers, Matthias Klinger, Jennifer E. Hundt, Jennifer E. Hundt   +14 more
doaj   +1 more source

Reassessing Remission in Pemphigus Vulgaris: Beyond Complete Remission Towards Meaningful Disease Control

International Journal of Dermatology, EarlyView.
ABSTRACT Current remission criteria for pemphigus vulgaris rely on binary, lesion‐based endpoints that do not capture immunological status, treatment toxicity, or patient quality of life. We argue for a multidimensional framework incorporating minimal disease activity, validated severity scores, glucocorticoid toxicity indices, and patient‐reported ...
Rhea Ahuja, Sumin Hong, Dédée F. Murrell   +2 more
wiley   +1 more source

Use of Domain-Swapped Molecules for Conformational Epitope Mapping of Desmoglein 3 in Pemphigus Vulgaris [PDF]

, 2000
Pemphigus vulgaris is an autoimmune blistering disease caused by autoantibodies against desmoglein 3, a member of the desmosomal cadherin family. These autoantibodies recognize conformation-dependent epitopes on desmoglein 3.
Nishikawa, Takeji, Fujii, Yoshiko, Nishifuji, Koji, Sekiguchi, Maiko, Futei, Yuko, Amagai, Masayuki   +5 more
core   +1 more source

Fogo selvagem: endemic pemphigus foliaceus [PDF]

Anais Brasileiros de Dermatologia, 2018
: Fogo selvagem or endemic pemphigus foliaceus is an autoimmune acantholytic anti-cadherin bullous disease that primarily affects seborrheic areas, which might disseminate.
Günter Hans-Filho, Valéria Aoki, Nelise Ritter Hans Bittner, Guilherme Canho Bittner   +3 more
doaj   +1 more source

Intercalated disk structure, tissue heterogeneity and ion channel distribution modulate conduction and local calcium influx

The Journal of Physiology, EarlyView.
Abstract figure legend A, three‐dimensional representation of cardiac intercalated disk, reduced to a 100‐partition, computationally efficient network representation. B, ion dynamics within intercalated disk extracellular cleft space. C, rapid pacing leads to localized conduction block in tissue with regions of perturbed intercalated disk (ID ...
Nicolae Moise, Heather L. Struckman, James W. Smyth, Gregory S. Hoeker, Steven Poelzing, Rengasayee Veeraraghavan, Seth H. Weinberg   +6 more
wiley   +1 more source