Evaluation of anti-desmoglein-1 and anti-desmoglein-3 autoantibody titers in pemphigus patients at the time of the initial diagnosis and after clinical remission. [PDF]
Medicine (Baltimore), 2017 It has been suggested that anti-desmoglein autoantibody titers could be helpful in follow-up and therapeutic management of pemphigus patients. However, there is no consensus regarding the relationship between anti-desmoglein autoantibody titers and ...
Russo I +3 more
europepmc +2 more sources
, 2022 Objective The aim of this study was to test the efficacy of autoantibodies to desmoglein 1 and desmoglein 3 detected by ELISA and indirect immunofluorescence in the diagnosis of oral pemphigus and to correlate the antibody titres with the severity of ...
Contaldo, Maria +14 more
core +2 more sources
Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion. [PDF]
, 2013 Desmosomes provide intercellular adhesive strength required for integrity of epithelial and some non-epithelial tissues. Within the epidermis, the cadherin-type adhesion molecules desmoglein (Dsg) 1-4 and desmocollin (Dsc) 1-3 build the adhesive core of ...
Bettina Kempf +17 more
core +2 more sources
Expression of Desmoglein 1 Compensates for Genetic Loss of Desmoglein 3 in Keratinocyte Adhesion [PDF]
, 2002 The desmoglein compensation hypothesis, namely that one desmoglein can compensate for loss of function of another, has been proposed to explain the tissue specificity of the autoantibody-induced loss of cell adhesion in pemphigus.
Stanley, John R. +2 more
core +1 more source
Staphylococcal Exfoliative Toxin B Specifically Cleaves Desmoglein 1 [PDF]
, 2002 Staphylococcal scalded skin syndrome and its localized form, bullous impetigo, show superficial epidermal blister formation caused by exfoliative toxin A or B produced by Staphylococcus aureus.
Stanley, John R. +11 more
core +1 more source
Indian Journal of Dermatology, 2016 Pemphigus vulgaris (PV) is an autoimmune blistering disease elicited by anti-desmoglein (DsG) 3 antibody. Although skin lesions tend to be distributed over the entire body, in some patients, they are confined to a restricted area.
Asuka Yoshifuku +7 more
doaj +1 more source
The Anti-Desmoglein 1 Autoantibodies in Pemphigus Vulgaris Sera are Pathogenic [PDF]
, 1999 Pemphigus vulgaris and pemphigus foliaceus are two closely related, but clinically and histologically distinct, autoimmune skin diseases. The autoantigens for pemphigus vulgaris and pemphigus foliaceus are desmoglein 3 and desmoglein 1, respectively. The
Ding, Xiang +4 more
core +1 more source
, 2010 Review on DSG2 (desmoglein 2), with data on DNA, on the protein encoded, and where the gene is ...
M Yashiro, Yashiro, M
core +1 more source
From Insect Bites to a Skin Autoimmune Disease: A Conceivable Pathway to Endemic Pemphigus Foliaceus
Frontiers in Immunology, 2022 In the endemic variants of pemphigus foliaceus (PF), in Brazil and Tunisia, patients generate pathogenic IgG4 anti-desmoglein 1 autoantibodies. Additionally, these patients possess antibodies against salivary proteins from sand flies that react with Dsg1,
Ning Li +5 more
doaj +1 more source
Bullous pemphigoid associated with milia, increased serum IgE, autoantibodies against desmogleins, and refractory treatment in a young patient [PDF]
Anais Brasileiros de Dermatologia, 2017 : Bullous pemphigoid is a blistering autoimmune disease characterized by two hemidesmosomal proteins (anti-BP180 and 230). Pemphigus, by contrast, is characterized by two autoantibodies (anti-desmoglein 1 and 3).
Shu Ding +5 more
doaj +1 more source