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Dental Clinics of North America, 2005
Pemphigus is an umbrella term for more than 10 different epidermal disease types and subtypes currently classified under this name. Characteristic for pemphigus are the presence of autoantibodies against epidermal cell adhesion structures (desmosomes), leading to a breakdown of cutaneous and mucosal barriers.
Jean-Claude, Bystryn+1 more
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Pemphigus is an umbrella term for more than 10 different epidermal disease types and subtypes currently classified under this name. Characteristic for pemphigus are the presence of autoantibodies against epidermal cell adhesion structures (desmosomes), leading to a breakdown of cutaneous and mucosal barriers.
Jean-Claude, Bystryn+1 more
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The Lancet, 2019
Pemphigus consists of a group of rare and severe autoimmune blistering diseases mediated by pathogenic autoantibodies mainly directed against two desmosomal adhesion proteins, desmoglein (Dsg)1 and Dsg3 (also known as DG1 and DG3), which are present in the skin and surface-close mucosae.
Schmidt, Enno+2 more
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Pemphigus consists of a group of rare and severe autoimmune blistering diseases mediated by pathogenic autoantibodies mainly directed against two desmosomal adhesion proteins, desmoglein (Dsg)1 and Dsg3 (also known as DG1 and DG3), which are present in the skin and surface-close mucosae.
Schmidt, Enno+2 more
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Pemphigus Vulgaris and Paraneoplastic Pemphigus
Oral and Maxillofacial Surgery Clinics of North America, 2008The history, epidemiology, pathophysiology, clinical presentation, diagnostic work-up, histopathology, and treatment of PV and PNP have been presented. These life-threatening, autoimmune, mucocutaneous bullous conditions may be encountered first by oral health providers and, therefore, deserve keen understanding and attention by the oral and ...
Ronald E. Grimwood+2 more
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Dermatologic Clinics, 1988
The term pemphigus refers to a group of autoimmune intraepidermal blistering diseases of the skin and mucous membranes. Several clinical variants of pemphigus are recognized. The major histologic feature of all variants is acantholysis, the disruption of normal cell-to-cell adhesion, which leads to intraepidermal blister formation.
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The term pemphigus refers to a group of autoimmune intraepidermal blistering diseases of the skin and mucous membranes. Several clinical variants of pemphigus are recognized. The major histologic feature of all variants is acantholysis, the disruption of normal cell-to-cell adhesion, which leads to intraepidermal blister formation.
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Pemphigus: Pemphigus vulgaris and pemphigus foliaceus
1990The term pemphigus stems from the Greek pemphix (blister) [1] and describes a group of chronic blistering skin diseases in which autoantibodies are directed against the cell surface of keratinocytes, resulting in the loss of cohesion between epidermal cells, through a process called acantholysis. Pemphigus is divided into pemphigus vulgaris (PV) with a
John R. Stanley, Stephan Müller
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La Presse Médicale, 2010
Pemphigus is a rare autoimmune blistering disorder involving the skin and mucosae. Three types of pemphigus have been described, including pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus. Diagnosis of the type of pemphigus is made by the combination of clinical features, histological and direct immunofluorescence findings, and ...
Hélène, Lapeyre-Liénard, Pascal, Joly
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Pemphigus is a rare autoimmune blistering disorder involving the skin and mucosae. Three types of pemphigus have been described, including pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus. Diagnosis of the type of pemphigus is made by the combination of clinical features, histological and direct immunofluorescence findings, and ...
Hélène, Lapeyre-Liénard, Pascal, Joly
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Orvosi Hetilap, 2007
A paraneoplasticus pemphigus malignus vagy benignus tumorokhoz társuló autoimmun hólyagos megbetegedés diagnosztikus és immunológiai kritériumait 1990-ben fektette le Anhalt . Klinikailag súlyos, fájdalmas, mélyre terjedő bőr- és nyálkahártyatünetek jellemzik. A bőrtünetek polimorf jellegűek, általában dominál a hólyagképződés.
Preisz, Klaudia, Kárpáti, Sarolta
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A paraneoplasticus pemphigus malignus vagy benignus tumorokhoz társuló autoimmun hólyagos megbetegedés diagnosztikus és immunológiai kritériumait 1990-ben fektette le Anhalt . Klinikailag súlyos, fájdalmas, mélyre terjedő bőr- és nyálkahártyatünetek jellemzik. A bőrtünetek polimorf jellegűek, általában dominál a hólyagképződés.
Preisz, Klaudia, Kárpáti, Sarolta
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Journal of the European Academy of Dermatology and Venereology, 2008
AbstractPemphigus refers to a group of potentially life‐threatening autoimmune diseases of the skin and mucous membranes, characterized by the formation of blisters and erosions of the skin. An autoimmune process, directed against keratinocyte desmosomal cadherins, interferes with the adhesive function of these molecules. This results in the separation
D, Ioannides+2 more
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AbstractPemphigus refers to a group of potentially life‐threatening autoimmune diseases of the skin and mucous membranes, characterized by the formation of blisters and erosions of the skin. An autoimmune process, directed against keratinocyte desmosomal cadherins, interferes with the adhesive function of these molecules. This results in the separation
D, Ioannides+2 more
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Immunotherapy, 2017
Pemphigus is a severe autoimmune blistering disease mediated by pathogenic anti-desmoglein antibodies leading to an inter keratinocyte disjunction. Rituximab is a monoclonal antibody that binds to the CD-20 antigen of B lymphocytes, which causes B-cell depletion and a subsequent reduction in pathogenic autoantibodies.
Vivien Hébert, Pascal Joly
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Pemphigus is a severe autoimmune blistering disease mediated by pathogenic anti-desmoglein antibodies leading to an inter keratinocyte disjunction. Rituximab is a monoclonal antibody that binds to the CD-20 antigen of B lymphocytes, which causes B-cell depletion and a subsequent reduction in pathogenic autoantibodies.
Vivien Hébert, Pascal Joly
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HERPETIFORM PEMPHIGUS, A VARIABLE PATTERN OF PEMPHIGUS
International Journal of Dermatology, 1975ABSTRACT: A patient with the clinical features of dermatitis herpetiformis and the histological features of pemphigus, subcorneal dermatosis and dermatitis herpetiformis did not respond to treatment with pyridine or sulfones. Systemic steroids and azothioprine were effective. Immunofluorescence studies demonstrated circulating pemphigus antibodies and
Stefania Jablonska+3 more
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