Results 61 to 70 of about 2,406 (225)

JAK Inhibitors as a Novel Approach to Autoimmune Bullous Diseases: A Review

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Autoimmune bullous diseases (AIBDs) are a group of chronic disorders characterized by blister formation resulting from abnormal immune responses. Janus kinase (JAK) inhibitors have emerged as promising therapeutic agents for AIBDs. This review discusses the use of JAK inhibitors—such as upadacitinib, baricitinib, tofacitinib, and abrocitinib, among ...
Olga Olisova, Yuliya Kolesova, Natalia Teplyuk, Ekaterina Grekova, Leyi Ni, Alina Mardanova, Karim Karray, Anastasiia Tikhonova, Anfisa Lepekhova, Jaime Piquero-Casals   +9 more
wiley   +1 more source

Epidemiology of Pemphigus in Morocco

JEADV Clinical Practice, Volume 4, Issue 5, Page 1114-1117, December 2025.
ABSTRACT Background The global distribution of pemphigus varies according to genetic, ethnic, socioeconomic, and cultural backgrounds. Despite the increased utilization of global health records and reporting systems, epidemiological data remain limited and poorly categorized.
Amani Fliti, Meryem Elomari Alaoui, Hanane Baybay, Fatima Zahra Mernissi, Fouzia Hali, Soumiya Chiheb, Nada Zizi, Siham Dikhaye, Ouafa Hocar, Amal Said, Ghita Basri, Fatima Zahra Agharbi, Hicham Titou, Naoufal Hjira, Ouiame El Jouari, Salim Gallouj, Mohamed Ait Ourhroui, Radia Chakiri, Jalal Elbenaye, Laila Benzekri, Karima Senouci   +20 more
wiley   +1 more source

Histomorphologic and Direct Immunofluorescence Findings of Autoimmune Bullous Disease [PDF]

, 2018
Autoimmune bullous diseases mainly present with vesiculobullous reaction pattern. First algorithm to approach skin biopsy of autoimmune vesiculobullous disease should be localization of the anatomic level of the split, which could be either ...
Ates, Deniz
core   +2 more sources

Incidence of Autoimmune Diseases in 30,340 Danish Women With Polycystic Ovary Syndrome (PCOS) Compared to 151,520 Controls. A National Cohort Study

Clinical Endocrinology, Volume 103, Issue 6, Page 863-872, December 2025.
ABSTRACT Objective Autoimmunity can be part of the pathogenesis of polycystic ovary syndrome (PCOS), but prospective studies on autoimmune disease in population based cohorts are lacking. This study aimed to investigate incidence rates of autoimmune disease in Danish women with PCOS before and after PCOS diagnosis compared to controls.
Dorte Glintborg, Jens‐Jakob Kjer Møller, Katrine Hass Rubin, Louise Lehmann Christensen, Marianne Skovsager Andersen   +4 more
wiley   +1 more source

Pemphigus: Subtypes, Clinical Features, Diagnosis, and Treatment [PDF]

, 2017
Pemphigus is a group of autoimmune blistering disorders associated with autoantibodies against the keratinocyte cell surface. Pemphigus has three major variants: pemphigus vulgaris (PV), pemphigus foliaceus (PF), and paraneoplastic pemphigus (PNP) which ...
Kilic, Arzu
core   +1 more source

Quality of life index in autoimmune bullous dermatosis patients [PDF]

Anais Brasileiros de Dermatologia, 2015
BACKGROUND: Autoimmune bullous dermatoses are complex diseases triggered by autoantibodies action against epidermal antigens or the dermoepidermal junction. Blisters and vesicles that evolve with erosion areas characterize them.
Mariana Álvares Penha, Joyce Godoy Farat, Hélio Amante Miot, Sílvia Regina Catharino Sartori Barraviera   +3 more
doaj   +1 more source

Real‐Time, Noninvasive Diagnosis of Bullous Pemphigoid: Diagnostic Performance of Line‐Field Confocal Optical Coherence Tomography

Skin Research and Technology, Volume 31, Issue 9, September 2025.
ABSTRACT Background Bullous pemphigoid (BP) is a common autoimmune blistering dermatosis often difficult to distinguish from other inflammatory conditions. Timely diagnosis is crucial for appropriate management. Line‐field confocal optical coherence tomography (LC‐OCT), a noninvasive imaging technique that uses an 800nm laser to generate high ...
Frank Friedrich Gellrich, Samal Rakhmetova, Claudia Günther, Stefan Beissert, Sarah Hobelsberger   +4 more
wiley   +1 more source

A Cross-sectional Study of Clinical, Histopathological and Direct Immunofluorescence Spectrum of Vesiculobullous Disorders [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Accurate diagnosis of vesiculobullous lesions of skin requires evaluation of clinical, histopathologic and immunofluorescence findings. Methods: A cross-sectional study of 68 patients to evaluate the clinical, histopathological and direct
Arundhathi S., Ragunatha S., Mahadeva K.C.   +2 more
doaj   +1 more source

A comparative study of expression of Fc receptors in relation to the autoantibody-mediated immune response and neutrophil elastase expression in autoimmune blistering dermatoses

Polish Journal of Pathology, 2017
Here we investigated the cutaneous CD32A and CD89 expression in relation to the neutrophil elastase (NE) expression and serum level of anti-desmoglein 1 and 3 (DSG1/DSG3) IgG in pemphigus, anti-BP180/BP230 IgG in bullous pemphigoid (BP), anti-gliadin ...
Justyna Gornowicz-Porowska, Agnieszka Seraszek-Jaros, Monika Bowszyc-Dmochowska, Elżbieta Kaczmarek, Paweł Pietkiewicz, Paweł Bartkiewicz, Marian Dmochowski   +6 more
doaj   +1 more source

Retrospective analysis of autoimmune bullous diseases in Middle Franconia

Frontiers in Immunology, 2023
IntroductionAutoimmune bullous diseases (AIBDs) are a group of rare cutaneous disorders affecting cornified skin and mucous membranes. They are characterized by tense or flaccid blistering and erosions due to autoantibodies against desmosomal and ...
Lukas Sollfrank, Lukas Sollfrank, Valerie Schönfelder, Valerie Schönfelder, Micheal Sticherling, Micheal Sticherling   +5 more
doaj   +1 more source