Results 111 to 120 of about 243,101 (317)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Main issues in penetrating keratoplasty

open access: yesTaiwan Journal of Ophthalmology
This review explores contemporary challenges in penetrating keratoplasty (PK), focusing on technical intricacies, technological advancements, and strategies for preventing graft rejection. A systematic literature search from January 2018 to July 2023 was
Jorge L Alió   +5 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

The Antimicrobial and Antiviral Applications of Cell-Penetrating Peptides

open access: yes, 2015
Over the past two decades, cell-penetrating peptides (CPPs) have become increasingly popular both in research and in application. There have been numerous studies on the physiochemical characteristics and behavior of CPPs in various environments ...
Eriste, Elo   +5 more
core   +1 more source

Thoracic trauma: analysis of 100 consecutive cases [PDF]

open access: yesEinstein (São Paulo), 2010
Objective: To analyze thoracic trauma assisted by the EmergencyService of Hospital da Irmandade da Santa Casa de Misericórdia deSão Paulo. Methods: One hundred patients with thoracic trauma wereassisted throughout six months in 2006.
Maíra Benito Scapolan   +6 more
doaj  

Multiple-Projectile Penetrating Neck Injury from a Modified Nail-Containing Gas Pistol

open access: yesBalkan Medical Journal, 2014
Background: Penetrating neck injuries result from missiles and stab wounds. A gas pistol is a non-lethal weapon for self-defence. Case Report: We present a case where the use of a modified gun led to multiple injuries in a single shot.
Dimitar Dimitrov Pazardzhikliev
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Microwave detection of buried mines using non-contact, synthetic near-field focusing

open access: yes, 2001
Existing ground penetrating radars (GPR) are limited in their 3-D resolution. For the detection of buried land-mines, their performance is also seriously restricted by `clutter'. Previous work by the authors has concentrated on removing these limitations
McCutcheon, E   +8 more
core   +1 more source

Contact lenses for visual rehabilitation in post-keratoplasty eyes: A review

open access: yesIndian Journal of Ophthalmology
To assess the role of various types of contact lenses (CL) after penetrating and lamellar keratoplasty, we reviewed all studies that were related to CL fitting in post-keratoplasty (full-thickness and lamellar) eyes between 1990 and 2024 by using ...
Mohamed Ibrahime Asif   +5 more
doaj   +1 more source

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