Results 41 to 50 of about 601,393 (323)

Confocal microscopy as an aid in the diagnosis of keratitis due to Candida parapsilosis [PDF]

Revista Brasileira de Oftalmologia
To describe a case of treatment-resistant corneal infiltrate in a patient 4 months after penetrating keratoplasty. The etiological diagnosis was established through microbiology and in vivo corneal confocal microscopy.
Bianca Luiza Valduga Guareschi, Clainijane Ramalho Borges, Paula Kataguiri, Tadeu Cvintal, Victor Cvintal, Bret Alan Moore, Fabiano Montiani Ferreira   +6 more
doaj   +1 more source

TeV Neutrinos from Successful and Choked Gamma-Ray Bursts

, 2001
Core collapse of massive stars resulting in a relativistic fireball jet which breaks through the stellar envelope is a widely discussed scenario for gamma-ray burst production. For very extended or slow rotating stars, the fireball may be unable to break
B. Paczyński, B. Paczyński, C. Kouveliotou, E. Andres, E. Costa, E. V. Derishev, E. Waxman, E. Waxman, E. Waxman, E. Waxman, E. Waxman, Eli Waxman, F. Halzen, G. J. Fishman, J. Alvarez-Muniz, J. C. Wheeler, J. Goodman, J. N. Bahcall, J. Rachen, J. Tan, L. Wang, M. Aloy, M. Vietri, P. Mészáros, P. Mészáros, P. Mészáros, Peter Mészáros, R. Blandford, R. Cen, S. Woosley, T. Gaisser   +30 more
core   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Low-gravity penetrometry of asteroids and comets [PDF]

, 2006
Extract from introduction: There are a number of contexts in which space hardware may interact mechanically with the solid material present in a low-gravity environment at the surface of an asteroid or comet, possibly penetrating to some depth and ...
Ball, Andrew J.
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

An uncommon cause of death in a pedal cyclist

Sri Lanka Journal of Medicine, 2017
Correction: On 16th February 2017, the author  K. Peiris was removed from this paper. The author had been inadvertently included. This error is regretted.
D.M.G. Fernando, K.M.P.L. Dayaratne, B.G. Premaratne   +2 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Perturbations of the Kerr spacetime in horizon penetrating coordinates [PDF]

, 2000
We derive the Teukolsky equation for perturbations of a Kerr spacetime when the spacetime metric is written in either ingoing or outgoing Kerr-Schild form.
Baker J, Campanelli M, Gaurav Khanna, Jorge Pullin, Manuela Campanelli, Michael P Ryan, Pablo Laguna, Pullin J   +7 more
core   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source