Results 51 to 60 of about 563,263 (296)

Cell-Penetrating Peptides, Electroporation, and Drug Delivery

, 2010
Certain short polycations, such as TAT and oligoarginine, rapidly pass through the plasma membranes of mammalian cells by a mechanism called transduction, as well as by endocytosis and macropinocytosis.
Cahill, Kevin
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Patterns of ocular trauma among the elderly in a South-American urban area and the association between eye traumas with sleep disorders

Journal of Emergencies, Trauma and Shock, 2017
Aims: Eye trauma in the older population can lead to blindness. Sleep deterioration is associated with increased risk of occupational injuries. The purpose of the study was to assess the epidemiology of ocular trauma in the elderly population and to ...
Sergio Henrique N Moreira, Niro Kasahara
doaj   +1 more source

Oncological outcomes of Crohn's disease‐associated cancers focusing on disease behavior

Annals of Gastroenterological Surgery, 2023
Background The overall risk of colorectal cancer in Crohn's disease (CD) is higher than in the general population, and CD‐associated cancer (CDAC) has poorer prognosis than sporadic cancer.
Akira Yamamoto, Yuji Toiyama, Hiroki Ikeuchi, Motoi Uchino, Kitaro Futami, Kinya Okamoto, Takayuki Ogino, Soichiro Ishihara, Yoichi Ajioka, Kenichi Sugihara, for the Study Group for Inflammatory Bowel Disease Associated Intestinal Cancers by the Japanese Society for Cancer of the Colon and Rectum   +10 more
doaj   +1 more source

Flowmeter and Ground Penetrating Radar: comparison between hydrogeological and geophysical methods [PDF]

, 2012
We discuss a comparison between saturated hydraulic conductivity calculated with Electromagnetic Borehole Flowmeter (EBF) and water content obtained by Ground Penetrating Radar (GPR) Zero Offset Profile ...
Arato, Alessandro, Basirico’, S., Crosta, G.B., Frattini, P., Godio, Alberto, Villa, Alberto   +5 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Fever of Unknown Origin and Penetrating Aortic Ulcer Successfully Treated with Thoracic Endovascular Aortic Repair—A Case Report

Diagnostics
Background and Clinical Significance: Fever of undetermined origin (FUO is a diagnostic challenge. It is essential to exclude infections, paraneoplastic syndromes, and large-vessel vasculitis (LVV).
Tomislav Jakljević, Franka Kunovac, Tatjana Zekić, Vjekoslav Tomulić   +3 more
doaj   +1 more source

Delayed diagnosis of traumatic ventricular septal perforation in penetrating chest injury: hematoma formation in the ventricular septum in CT suggests perforation

Acute Medicine & Surgery, 2019
Background Ventricular septal perforation (VSP) can be caused by a penetrating cardiac injury. Diagnosis of VSP tends to be delayed because a shunt might not be detected by color flow Doppler at an early stage following injury.
Nobuki Shioya, Nozomu Inoue, Harutatsu Muto, Akiko Tomita, Yuki Tsukamoto, Naonori Kawashima, Koji Hazama, Yasuo Shichinohe   +7 more
doaj   +1 more source

Fatores prognósticos nos ferimentos cervicais penetrantes Prognostic factors of penetrating neck trauma

Brazilian Journal of Otorhinolaryngology, 2011
O pescoço é vulnerável a traumatismos devido à grande quantidade de estruturas vitais, podendo ocorrer lesões importantes e com alta morbimortalidade. OBJETIVO: Avaliar resultados em pacientes vítimas de ferimentos penetrantes cervicais.
José Cruvinel Neto, Rogério Aparecido Dedivitis   +1 more
doaj   +1 more source

An unusual impalement injury to knee

Journal of Dr. NTR University of Health Sciences, 2020
Impalement injuries are one of the severe types of injuries combining effects of both penetrating and blunt trauma leading to crushing injury, wound contamination, and multi-organ damage.
Hitesh A R. Kodidasu, Arun K Murugan, Chandra Sekhar Siddanathi, Ashok K Patnala   +3 more
doaj   +1 more source