Results 71 to 80 of about 563,263 (296)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Pediatric upper extremity fence-penetrating traumas

Turkish Journal of Plastic Surgery, 2018
Purpose: Penetrating hand injuries related to sharp metal or wooden fences are rarely reported in pediatric population. Most of these traumas occur after accidentally falling on the fence.
Musa Kemal Keles, Ugur Horoz, Bugçe Ballioglu, Hatice Gözde Muratoglu, Ergin Seven, Ali Teoman Tellioglu   +5 more
doaj   +1 more source

Endovascular treatment of carotid-cavernous fistula type A with platinium coils [PDF]

Vojnosanitetski Pregled, 2008
Background. Carotid-cavernous fistulas are abnormal communications between carotid arteries or their branches and the cavernous system caused mostly by trauma.
Ćulafić Slobodan, Juszkat Robert, Rusović Siniša, Stefanović Dara, Minić Ljubodrag, Spaić Milan   +5 more
doaj   +1 more source

p-Branes and the GZK Paradox

, 2002
In spacetimes with asymmetric extra dimensions, cosmic neutrino interactions may be extraordinarily enhanced by p-brane production. Brane formation and decay may then initiate showers deep in the Earth's atmosphere at rates far above the standard model ...
Ahn, Alvarez-Muniz, Anchordoqui, Anchordoqui, Anchordoqui, Antoniadis, Argyres, Arkani-Hamed, Banks, Barger, Cavaglià, Cullen, Dimopoulos, Dimopoulos, Eardley, Emparan, Emparan, Feng, Giddings, Giddings, Giddings, Giddings, Goldberg, Gregory, Greisen, Haim Goldberg, Hall, Hanhart, Hannestad, Hannestad, Hoyle, Jain, Jonathan L. Feng, Kowalski, Lai, Lee, Luis A. Anchordoqui, Lykken, Lykken, Myers, Protheroe, Protheroe, Randall, Ringwald, Sen, Sen, Shiu, Solodukhin, Tyler, Voloshin, Voloshin, Yoshida, Zatsepin   +52 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Traumatismos de veia cava inferior

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar a incidência, o perfil clínico e as estratégias operatórias dos ferimentos de Veia Cava Inferior (VCI). MÉTODOS: Foram analisados retrospectivamente os prontuários de 76 doentes com ferimento de VCI atendidos nos dois prontossocorros de
Cleinaldo de Almeida Costa, José Carlos Costa Baptista-Silva, Lana Márcia Esteves Rodrigues, Fabiana Lo Presti Mendonça, Thiago Silveira Paiva, Emil Burihan   +5 more
doaj   +1 more source

Abdominal trauma and Liver some Management Considerations after a Retrospective Study.

Albanian Journal of Trauma and Emergency Surgery, 2019
INTRODUCTION: The liver is the most frequently injured abdominal organ. Most of liver injuries are relatively minor and heal spontaneously with nonoperative management, which consists of observation and possibly arteriography and embolization. Purpose to
Agron Dogjani, Kastriot Haxhirexha
doaj   +1 more source

Shoprite in Malawi, Swaziland and Zambia: A Report by the Bench Marks Foundation [PDF]

, 2009
This report produces a number of penetrating findings which are presented in such a manner as to indicate both the change imperative required to support principles of empowerment and sustainable development through corporate social responsibility, and ...

core  

Molecular Structure Influences the Stability of Membrane Penetrating Biointerfaces. [PDF]

, 2011
20.07.15 KB. Ok to add accepted version, 12 months embargo expired.Nanoscale patterning of hydrophobic bands on otherwise hydrophilic surfaces allows integration of inorganic structures through biological membranes, reminiscent of transmembrane proteins.
Almquist, BD, Melosh, NA
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source