Results 71 to 80 of about 243,101 (317)

Recurrent Ectasia After Penetrating Keratoplasty

, 2013
Corneal ectasia or recurrent keratoconus after penetrating keratoplasty is rare, and few case reports exist in the literature concerning this condition. Computerized corneal topography is quite useful to identify and manage this disorder.
Firdevs Örnek, Züleyha Yalnız Akkaya, Koray Budak, Ayşe Burcu   +3 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

A tomographic inversion approach for the detection of decay and cavities in tree trunks using ground penetrating radar

, 2019
A variety of tree species, such as ash and oak trees, are nowadays under serious threat in the United Kingdom and European territories as a result of the action of aggressive fungal diseases. To this effect, Ground Penetrating Radar (GPR) is an effective
Catapano, Ilaria, Gennarelli, Gianluca, Alani, Amir M., Soldovieri, Francesco, I. Catapano, Tosti, Fabio, L. Lantini, A. M. Alani, I. Giannakis, F. Tosti, G. Ludeno, G. Gennarelli, Giannakis, Iraklis, Lantini, Livia, Alani, Amir, Ludeno, Giovanni, F. Soldovieri   +16 more
core   +1 more source

Engineered Probiotic‐Powered Micro‐Rod Robot Bomb for Thrombus‐Penetrating Explosion

Advanced Science
Conventional thrombolytic agents demonstrated limited efficacy in treating thrombotic disorders characterized by narrow therapeutic windows and progressive vascular injury, lacking the required precision, timeliness, and treatment durability.
Riyue Liu, Jiale Chen, Yuanyuan Li, Nawsherwan, Cuilian Dai, Yan Wang, Jinrong Zheng, Kecheng Zhou, Mangmang Sang   +8 more
doaj   +1 more source

Penetrating thoracoabdominal injuries from multiple‐spiked spear stabbing: Case report and literature review

Clinical Case Reports, 2020
Penetrating thoracoabdominal injuries carry high morbidity and mortality. Concurrent clinical evaluation and resuscitation followed by early surgery are associated with good outcome.
David Muchuweti, Edwin Muguti
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A 2D processing algorithm for detecting landmines using Ground Penetrating Radar data [PDF]

, 2012
Ground Penetrating Radar(GPR) is one of a number of technologies that have been used to improve landmine detection efficiency. The clutter environment within the first few cm of the soil where landmines are buried, exhibits strong reflections with ...
Cockshott, W.P., Sengodan, A.
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

A novel processing framework for tree root mapping and density estimation using ground penetrating radar

, 2019
Estimating the root density of mature trees is of high importance as the root system is a robust indicator of both the health status and the structural integrity of a tree.
Andrea Benedetto, Benedetto, Andrea, Alani, Amir M., Tosti, Fabio, Amir M. Alani, Giannakis, Iraklis, Lantini, Livia, Fabio Tosti, Alani, Amir, Daniel Egyir, Egyir, Daniel, Iraklis Giannakis, Livia Lantini   +12 more
core   +1 more source

Traumatismos de veia cava inferior

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar a incidência, o perfil clínico e as estratégias operatórias dos ferimentos de Veia Cava Inferior (VCI). MÉTODOS: Foram analisados retrospectivamente os prontuários de 76 doentes com ferimento de VCI atendidos nos dois prontossocorros de
Cleinaldo de Almeida Costa, José Carlos Costa Baptista-Silva, Lana Márcia Esteves Rodrigues, Fabiana Lo Presti Mendonça, Thiago Silveira Paiva, Emil Burihan   +5 more
doaj   +1 more source