Results 61 to 70 of about 243,101 (317)

Fatores prognósticos nos ferimentos cervicais penetrantes Prognostic factors of penetrating neck trauma

open access: yesBrazilian Journal of Otorhinolaryngology, 2011
O pescoço é vulnerável a traumatismos devido à grande quantidade de estruturas vitais, podendo ocorrer lesões importantes e com alta morbimortalidade. OBJETIVO: Avaliar resultados em pacientes vítimas de ferimentos penetrantes cervicais.
José Cruvinel Neto   +1 more
doaj   +1 more source

How do current police practices impact trauma care in the prehospital setting? A scoping review

open access: yesJournal of the American College of Emergency Physicians Open, 2023
Objective In the United States, police are often important co‐responders to 911 calls with emergency medical services for medical emergencies. To date, there remains a lack of a comprehensive understanding of the mechanisms by which police response ...
Rama A. Salhi   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Robust penetrating microelectrodes for neural interfaces realized by titanium micromachining

open access: yes, 2011
Neural prosthetic interfaces based upon penetrating microelectrode devices have broadened our understanding of the brain and have shown promise for restoring neurological functions lost to disease, stroke, or injury.
Patrick T. McCarthy   +8 more
core   +1 more source

The Burden of Liver Trauma in an Urban Trauma Centre in Johannesburg, South Africa

open access: yesTrauma Care
Background: Liver trauma is prevalent following blunt and penetrating injuries. This study examined liver trauma in a South African urban trauma centre, focusing on the unique prevalence of penetrating injuries and surgical interventions.
Isabella Margaretha Joubert   +3 more
doaj   +1 more source

Preoperative evaluation of penetrating esophageal trauma in the current era: An analysis of the National Trauma Data Bank

open access: yesJournal of Emergencies, Trauma and Shock, 2015
Background: Preoperative diagnostic evaluation (PDE) of penetrating esophageal injury (PeEsIn) can delay treatment and increase morbidity. We sought to study the relationship among PDE, delay in definitive treatment, and patient mortality in PeEsIn ...
Daniel Dante Yeh   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Penetrating Cardiac Injuries

open access: yes, 2010
Objective:Penetrating cardiac injuries have high mortality rates due to serious clinical outcomes. This study was planned to evaluate patients with penetrating cardiac injury.Material and methods:We reviewed the records of patients who were operated ...
Aziz Mutlu Barlas   +5 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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