Results 131 to 140 of about 802,819 (312)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Thermal Cone Penetration Test (T-CPT)

, 2018
The Thermal Cone Penetration Test (T-CPT) records temperature dissipation during an interruption of the Cone Penetration Test (CPT) to determine the thermal properties of the ground, taking advantage of heat generated in the cone penetrometer during ...
Vardon, P.J. (author), Baltoukas, Dimitris (author), Peuchen, Joek (author)   +2 more
core  

Numerical Simulation Study on the Effect of the Wave Shaper on Shaped Charge Jet Formation in Centrally-Aperture Liners

Gaoya wuli xuebao
To investigate the role of wave shapers in small-caliber shaped charges, the effects of aligning wave shaper parameters with those of center-holed liners on detonation product leakage and jet penetration performance were studied.
Zhouguang LIANG, Jianping FU, Kai REN, Rui YANG, Junqing SHI, Bo WANG, Yueguang GAO, Zhigang CHEN   +7 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Investigation of tool geometry effect and penetration strategies on cutting forces during thread milling [PDF]

, 2014
The application of thread milling is increasing in industry because of its inherent advantages over other thread cutting techniques. The objective of this study is to investigate the effect of milling cutter tool geometry on cutting forces during thread ...
Sharma, Vishal S., FROMENTIN, Guillaume, POULACHON, Gerard, BRENDLEN, Romain, SHARMA, Vishal   +4 more
core  

Development of an Epidermal Growth Factor (EGF) Loaded Elastosome Formulation for Enhanced Skin Penetration and Anti-Aging Effects

Cosmetics
Achieving optimal skin penetration with bioactive cosmetic ingredients, such as epidermal growth factor (EGF), presents ongoing challenges. This study introduces a novel elastosome-based EGF delivery system co-loading dexpanthenol, which achieves ...
Seul Gi Heo, Won Kyu Hong, Eun Mi Kim, Min Soo Kim, Si Young Song, Su Mi Choi, Jun Hyeong Park, Ji Hye Kim, Gwang Seong Choi   +8 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Hyaluronic Acid in Topical Applications: The Various Forms and Biological Effects of a Hero Molecule in the Cosmetics Industry

Biomolecules
Background: Hyaluronan, or hyaluronic acid (HA), is a glycosaminoglycan with structural and signaling functions playing key roles in human skin homeostasis.
Catherine Zanchetta, Amandine Scandolera, Romain Reynaud   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source