Results 121 to 130 of about 14,954,259 (382)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Application of cone penetration test (CPT) results for soil classification

open access: yesGrađevinar, 2017
The paper presents an application of CPT results for soil classification according to Unified Soil Classification System (USCS) and European Soil Classification System (ESCS) by using computer program KLASIF.
Lovorka Librić   +2 more
doaj   +1 more source

PENETRATION TESTING

open access: yes, 2023
This slide deck provides a deep dive into penetration testing with a focus on the capabilities of Kali Linux. The slides begin with an overview and then divide into information gathering, vulnerability analysis, exploitation, and post-exploitation tools.
openaire   +1 more source

On protection of Freedom's solar dynamic radiator from the orbital debris environment. Part 2: Further testing and analyses [PDF]

open access: yes
Presented here are results of a test program undertaken to further define the response of the solar dynamic radiator to hypervelocity impact (HVI). Tests were conducted on representative radiator panels (under ambient, nonoperating conditions) over a ...
Christiansen, Eric L.   +2 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Needle penetration test - qualifying examination of 3D printable silicones for vascular models in surgical practice. [PDF]

open access: yes3D Print Med, 2021
von Steuben T   +4 more
europepmc   +1 more source

Experimental study of ceramic coated tip seals for turbojet engines [PDF]

open access: yes
Ceramic gas-path seals were fabricated and successfully operated over 1000 cycles from flight idle to maximum power in a small turboshaft engine. The seals were fabricated by plasma spraying zirconia over a NiCoCrAlX bond boat on the Haynes 25 substrate.
Biesiadny, T. J.   +5 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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