Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Laboratory Testing of Kinetic Sand as a Reference Material for Physical Modelling of Cone Penetration Test with the Possibility of Artificial Neural Network Application. [PDF]
Materials (Basel), 2022 Gago F +3 more
europepmc +1 more source
Contestability, Technology and Banking [PDF]
We estimate the effect of internet penetration on retail bank margins in the euro area. Based on an adapted Baumol [1982] type contestability model, we argue that the internet has reduced sunk costs and therefore increased contestability in retail ...
Corvoisier, Sandrine +1 more
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Needle penetration test - qualifying examination of 3D printable silicones for vascular models in surgical practice. [PDF]
3D Print Med, 2021 von Steuben T +4 more
europepmc +1 more source
On protection of Freedom's solar dynamic radiator from the orbital debris environment. Part 2: Further testing and analyses [PDF]
Presented here are results of a test program undertaken to further define the response of the solar dynamic radiator to hypervelocity impact (HVI). Tests were conducted on representative radiator panels (under ambient, nonoperating conditions) over a ...
Christiansen, Eric L. +2 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Deformation parameters of soils determined by the cone penetration test
MATEC Web of Conferences, 2017 The article deals with the derivation of correlation relations from the cone penetration test, which are applied as input parameters in the calculations of advanced constitutive soil models.
Bulko Roman, Gago Filip
doaj +1 more source
Theoretical Studies and Implementation on the Temporary Data Storage Method for Cone Penetration Test. [PDF]
Sensors (Basel), 2021 Li Y +5 more
europepmc +1 more source