Results 81 to 90 of about 853,266 (286)

Damage to metallic samples produced by measured lightning currents [PDF]

open access: yes, 1991
A total of 10 sample disks of 2024-T3 aluminum and 4130 ferrous steel were exposed to rocket-triggered lightning currents at the Kennedy Space Center test site.
Fisher, Richard J., Schnetzer, George H.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Cone Penetration Testing 2022

open access: yes, 2022
The volume contains the proceedings of the 5th International Symposium on Cone Penetration Testing (CPT’22), held in Bologna, Italy, 8-10 June 2022. More than 450 authors -academics, researchers, practitioners and manufacturers – contributed to the peer-reviewed papers included in this book, which includes three keynote lectures, four invited lectures ...
G. Gottardi, L. Tonni
openaire   +2 more sources

ANALISIS POTENSI LIKUIFAKSI AKIBAT GEMPA BUMI DENGAN MENGGUNAKAN METODE STANDARD PENETRATION TEST DAN CONE PENETRATION TEST DI KABUPATEN BANTUL, YOGYAKARTA [PDF]

open access: yes, 2016
Gempa bumi yang terjadi di daerah Bantul, Yogyakarta pada 27 Mei 2006 dengan magnitudo gempa bumi sebesar 6.3 SR dapat menyebabkan terjadinya bahaya likuifaksi yang dapat merusak bangunan khususnya di wilayah Bantul Yogyakarta. Investigasi geoteknik yang
_, Tini
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

SOLUTIONS FOR TEST OF SUPREM PENETRATION ABILITY OF COMPETITORS ON INTERNATIONAL MARKETS [PDF]

open access: yes
Globalization is a phenomenon that occurs extensively in the current period. Thisprocess entails extensive and the need to consider that entities survival depends on the ability toaccess external markets. The paper forms by diagnosis internationalization
Iuliana Cenar
core  

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