Results 81 to 90 of about 39,709 (281)

A method for human teratogen detection by geometrically confined cell differentiation and migration [PDF]

open access: yes, 2014
Unintended exposure to teratogenic compounds can lead to various birth defects; however current animal-based testing is limited by time, cost and high inter-species variability.
Toh, Yi-Chin   +3 more
core   +2 more sources

Chelation Therapy for Rare Earth Element Toxicity: Current Evidence, Challenges and Future Directions

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 1, January 2026.
ABSTRACT The accelerating integration of rare earth elements (REEs) in advanced technologies has generated rising concern over human exposure and the attendant toxicological risks. This review presents an up‐to‐date synthesis of current evidence on REE toxicity across multiple exposure pathways, including inhalation, ingestion and occupational contact,
Jose L. Domingo
wiley   +1 more source

Use of the painDETECT tool in rheumatoid arthritis suggests neuropathic and sensitization components in pain reporting. [PDF]

open access: yes, 2014
Rheumatoid arthritis (RA) is an inflammatory autoimmune condition typified by systemic inflammation targeted toward synovial joints. Inhibition of proinflammatory networks by disease-modifying antirheumatic drugs, eg, methotrexate and biologic therapies,
Ahmed, S   +4 more
core   +2 more sources

Manifestation of morphea in a patient with myasthenia gravis under therapy with zilucoplan

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Phoebe Wellmann   +3 more
wiley   +1 more source

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 1, Page 24-39, January 2026.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source

Tratamento Endovascular da Disseção Crónica Isolada da Aorta Abdominal [PDF]

open access: yes, 2016
Isolated acute abdominal aortic dissection is a relatively rare event. Its natural history is not fully understood and its optimal treatment is not established.
Almeida, R.   +3 more
core   +1 more source

Methanobactin rapidly facilitates biliary copper excretion in a Wilson disease rat model visualised by 64Cu PET/MRI

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 2, Page 268-279, January 2026.
Background and Purpose Methanobactins are peptides with high copper affinity and potential to treat Wilson disease. We examined how two methanobactins (ARBM101 and MB‐OB3b) affected copper handling in the LPP Atp7b−/− Wilson disease rat model, compared to penicillamine or saline, by 64Cu positron emission tomography/magnetic resonance imaging ...
Emilie Munk Lynderup   +11 more
wiley   +1 more source

Myasthenia Gravis Outcomes After Use of Statins and Other Contraindicated Treatments: Results From the French National Insurance Database

open access: yesEuropean Journal of Neurology, Volume 33, Issue 1, January 2026.
In this real‐world study among 14,459 adults with MG, exposure to any contraindicated treatment was not significantly associated with risk of ICU admission for MG but was associated with significantly higher risk of death. In contrast, statins were associated with a greater risk of ICU admission but a lower risk of death.
Guilhem Solé   +7 more
wiley   +1 more source

Drug-induced dermatomyositis after lacosamide: A case report. [PDF]

open access: yes, 2018
Here we describe a caseof a woman who had DM after treatment withlacosamide.
Gaffney, Rebecca G.   +2 more
core   +1 more source

Impact of FSH‐Induced Ovarian Stimulation on Oocyte Recovery and In Vitro Embryo Production in the Red Sindhi Cows

open access: yesReproduction in Domestic Animals, Volume 61, Issue 1, January 2026.
ABSTRACT Follicle‐stimulating hormone (FSH) plays an important role in regulating reproductive events, particularly follicular development and oocyte competence acquisition. Some studies using FSH protocols in zebu cattle were performed, but data regarding its application in the Red Sindhi breed are scarce and therefore warranted. In this context, this
Ivo Pivato   +4 more
wiley   +1 more source

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