Tribulus terrestris Fruit Extract: Bioactive Compounds, ADMET Analysis, and Molecular Docking with Penicillin-Binding Protein 2a Transpeptidase of Methicillin-Resistant Staphylococcus epidermidis. [PDF]
Curr Issues Mol BiolAlzahrani KJ.
europepmc +1 more source
Thiolated Polymers in 3D Bioprinting: Control of Gelation
Advanced Materials, EarlyView.Thiolated polymers are established as programmable bioinks for 3D bioprinting, integrating versatile crosslinking chemistries with redox‐responsive control. This work demonstrates how molecular design and external triggers define gelation kinetics, printability windows, and structural fidelity, enabling stable, high‐resolution constructs and advancing ...
Soheil Haddadzadegan +2 more
wiley +1 more source
Advanced Materials Interfaces, EarlyView.Hair keratin fibers inevitably deteriorate under UV exposure, heat, and dryness. A robust composite coating assembles delaminated Ti3C2 MXene nanosheets onto keratin surfaces through biocompatible metal‐polyphenol networks of EGCG. This hybrid layer simultaneously screens UV, dissipates heat, reinforces mechanical strength, suppresses static charge ...
Juyeon Kang +8 more
wiley +1 more source
Molecular Basis of Influence of A501X Mutations in Penicillin-Binding Protein 2 of Neisseria gonorrhoeae Strain 35/02 on Ceftriaxone Resistance. [PDF]
Int J Mol SciKrivitskaya AV +4 more
europepmc +1 more source
Development of Nanoflare Nanosensors for Monitoring Cellular Insulin mRNA in Beta Cells and Islets
Advanced Materials Technologies, EarlyView.This study presents the design and application of In2‐NF probes for detecting insulin mRNA in beta cells and islets. Using spherical nucleic acid‐coated gold nanoparticles, the probes offer strong fluorescent signals upon hybridization. Their performance is validated across 2D and 3D cultures and rat islets, demonstrating sensitive, real‐time mRNA ...
Yana Hu +7 more
wiley +1 more source
Biocatalytic cyclization of small macrolactams by a penicillin-binding protein-type thioesterase. [PDF]
Nat Chem BiolBudimir ZL +7 more
europepmc +1 more source
An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids
Advanced Materials Technologies, EarlyView.This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto +6 more
wiley +1 more source
Structural basis of Pseudomonas aeruginosa penicillin binding protein 3 inhibition by the siderophore-antibiotic cefiderocol. [PDF]
Chem SciSmith HG +7 more
europepmc +1 more source
Topography‐Regulated Screening Platform for Myoblast Contact Guidance
Advanced Materials Technologies, EarlyView.This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng +6 more
wiley +1 more source
Modification of the penicillin-binding-protein 3 as a source of resistance to broad-spectrum cephalosporins in Escherichia coli. [PDF]
J Antimicrob ChemotherFreire S +5 more
europepmc +1 more source