Results 271 to 280 of about 460,006 (298)

Penicillin-Binding Proteins of Gram-Negative Bacteria

Clinical Infectious Diseases, 1988
beta-Lactam antibiotics exert their antibacterial effects by inactivating the high-molecular-weight penicillin-binding proteins (PBPs) that are responsible for the final stages of peptidoglycan biosynthesis. The availability of the amino acid sequences of several low-molecular-weight PBPs, high-molecular-weight PBPs, and active-site serine beta ...
B G, Spratt, K D, Cromie
openaire   +2 more sources

Penicillin-Binding Protein 4

2013
David I. Roper, Jeremy J.R.H. Tame
openaire   +2 more sources

Penicillin-binding proteins of Streptococcus pneumoniae

Journal of Antimicrobial Chemotherapy, 1988
Penicillin-binding protein (PBP) patterns of penicillin-resistant laboratory-constructed transformants were compared with the PBP profiles of 26 clinical isolates of Streptococcus pneumoniae. For transformation studies DNA from a penicillin-resistant clinical isolate was used to transform a susceptible laboratory strain.
L J, Chalkley, H J, Koornhof
openaire   +2 more sources

Penicillin-binding proteins: evergreen drug targets

Current Opinion in Pharmacology, 2014
The penicillin-binding proteins (PBPs) are well known targets for the β-lactam antibiotics. They continue to be a focus of interest for pharmaceutical design, as exemplified by the number of new agents under clinical investigation as well as novel experimental molecules.
Frère, Jean-Marie, Page, Malcolm G. P.
openaire   +3 more sources

Penicillin-binding Protein

2006
openaire   +2 more sources

Deletion of penicillin-binding protein 5 (PBP5) sensitises Escherichia coli cells to β-lactam agents

International Journal of Antimicrobial Agents, 2010
Chiranjit Chowdhury, Anindya S Ghosh
exaly  

Penicillin-binding proteins of Bacteroides fragilis

Journal of Antimicrobial Chemotherapy, 1984
BOTTA GA, PRIVITERA, GAETANO PIERPAOLO, MENOZZI MG   +2 more
openaire   +3 more sources

Penicillin-binding Proteins

RCSB Protein Data Bank, 2002
openaire   +1 more source

Binding of (5S)-penicilloic acid to penicillin binding protein 3.

ACS Chemical Biology, 2013
S. van Berkel, J. Nettleship, Ivanhoe K. H. Leung, J. Brem, Hwanho Choi, D. Stuart, T. Claridge, M. McDonough, R. Owens, Jingshan Ren, C. Schofield   +10 more
semanticscholar   +1 more source

A gene fusion that localises the penicillin-binding domain of penicillin-binding protein 3 ofEscherichia coli

FEBS Letters, 1984
Brian G Spratt
exaly