Results 231 to 240 of about 637,867 (346)

Affinity of cefotiam for the alternative penicillin binding protein PBP3SAL used by Salmonella inside host eukaryotic cells. [PDF]

J Antimicrob Chemother, 2023
Cestero JJ, Castanheira S, González H, Zaragoza Ó, García-Del Portillo F.   +4 more
europepmc   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

Advanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks   +16 more
wiley   +1 more source

Dynamic Profiling of Penicillin-Binding Protein 2a (PBP2a)-Positive Extracellular Vesicles: Implications for Early Diagnosis and Treatment Monitoring of Methicillin-Resistant Staphylococcus Aureus Infections. [PDF]

J Extracell Vesicles
Gao Q, Zhou W, Shen Z, Chen T, Hu C, Dong L, Han D, Li M.   +7 more
europepmc   +1 more source

Penicillin Binding Protein 7/8 Is a Potential Drug Target in Carbapenem-Resistant Acinetobacter baumannii. [PDF]

Antimicrob Agents Chemother, 2023
Russo TA, Carlino-MacDonald U, Alvarado CL, Davies CJ, Barnes O, Trivedi G, Mathur P, Hutson A, Adams FG, Zang M, Ascari A, Eijkelkamp BA.   +11 more
europepmc   +1 more source

Synthesis and biochemical evaluation of new 3-amido-4-substituted monocyclic ß-lactams as inhibitors of penicillin-binding protein(s) [PDF]

Katarina Grabrijan, Nika Strašek Benedik, Alen Krajnc, Krištof Bozovičar, Damijan Knez, Matic Proj, Irena Zdovc, Izidor Sosič, Carlos Contreras‐Martel, Andréa Dessen, Martina Hrast, Stanislav Gobec   +11 more
openalex   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Development of phenyl-urea-based small molecules that target penicillin-binding protein 4. [PDF]

Chem Biol Drug Des
Gondil VS, Butman HS, Young M, Walsh DJ, Narkhede Y, Zeiler MJ, Crow AH, Carpenter ME, Mardikar A, Melander RJ, Wiest O, Dunman PM, Melander C.   +12 more
europepmc   +1 more source

THE POTENTIAL AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS OF JATROPHONE FROM JATROPHA PODAGRICA THROUGH MOLECULAR DYNAMIC INTERACTION WITH PENICILLIN-BINDING PROTEIN 2A: INSIGHTS FROM COMPUTATIONAL CHEMISTRY ANALYSIS

Trần Mạnh Hùng, Trương Phú Chí Hiếu, Nguyen Thị Thanh Van, Светлана Носкова, Phu Tran Vinh Pham   +4 more
openalex   +1 more source

Penicillin-binding proteins of Rhodopseudomonas sphaeroides and their membrane localization [PDF]

, 1981
W. D. Shepherd, Samuel Kaplan, J T Park
openalex   +1 more source

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source