Results 21 to 30 of about 4,762 (258)

New Data On Isopenicillin N Synthase And Peroxisome Co-Location In The Hyphal Cells Of Penicillium Chrysogenum PQ-96 – Pexophagy And Exocytosis

open access: yesPostępy Mikrobiologii, 2019
The machinery of antibiotic production by Penicillium chrysogenum PQ-96 is composed of co-located cytosolic and peroxisomal enzymes of the penicillin G biosynthesis pathway.
Kurzątkowski Wiesław   +4 more
doaj   +1 more source

Electrochemical Determination of Penicillin G in Cow Milk and pharmaceuticals in SDS/Acetate buffer

open access: yesInternational Journal of Electrochemical Science, 2021
Penicillin residues in animal food products like milk and meat has attracted great concern by health regulatory agencies due to their negative effects.
Joshua M. Sila   +4 more
doaj   +1 more source

THE INFLUENCE OF LEVETIRACTEAM AND DIAZEPAM ON PENICILLIN-INDUCED FOCAL EPILEPTIC ACTIVITY

open access: yesZaporožskij Medicinskij Žurnal, 2014
Aim. The power of epileptic foci and their life-span in Wistar rats (44 animals) were investigated under conditions of levetiracetam (30,0 and 130,0 mg/kg, i.p.) and diazepam (0,5 and 1,5 mg/kg, i.p.) treatment in acute experiments.
Т. N. Muratova
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Antimicrobial Activity of Penicillin G and N-acetylcystein on Planktonic and Sessile Cells of Streptococcus suis [PDF]

open access: yesPolish Journal of Microbiology, 2016
The aim of this study was to investigate the capacity of Streptococcus suis strains to form biofilms and to evaluate the antimicrobial activity of Penicillin G and N-acetylcystein (NAC) on both S. suis sessile and planktonic forms.
Ivette Espinosa   +4 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Degradation of Penicillin G contaminant in synthesized wastewater by Fenton-like reaction

open access: yesEngineering and Applied Science Research, 2022
The aim of this research was to investigate the degradation of Penicillin G (PEN G) in synthesized wastewater via a Fenton-like reaction. Calcium dioxide (CaO2) was used as an oxidant in the Fenton-like reaction.
Wiparat Nisapai   +6 more
doaj  

Degradation of Ampicillin and Penicillin G using Anodic Oxidation

open access: yesInternational Journal of Electrochemical Science, 2013
The degradation of ampicillin and penicillin G has been carried out by oxidation method using mixed metal oxides (MMO) electrodes as the anode. The objective of this paper was to study the electrochemical properties of several types of antibiotic drugs ...
Mohd Dzul Hakim Wirzal   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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