Results 31 to 40 of about 652,585 (263)

Degradation of Ampicillin and Penicillin G using Anodic Oxidation

open access: yesInternational Journal of Electrochemical Science, 2013
The degradation of ampicillin and penicillin G has been carried out by oxidation method using mixed metal oxides (MMO) electrodes as the anode. The objective of this paper was to study the electrochemical properties of several types of antibiotic drugs ...
Mohd Dzul Hakim Wirzal   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Resistensi Antibiotik terhadap Bakteri Escherichia coli yang Diisolasi dari Ayam Layer di Desa Sesaot Kabupaten Lombok Barat

open access: yesMedia Kedokteran Hewan, 2022
Resistensi antibiotik saat ini menjadi ancaman terbesar bagi kesehatan masyarakat global, sehingga WHO mengkoordinasi kampanye global untuk meningkatkan kesadaran masyarakat terhadap antibiotik.
Alfiana Laili Dwi Agustin   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

ESTUDO EXPERIMENTAL DAS RELAÇÕES TECLDUAIS EM RATOS, PROVOCADAS POR DIFERENTES CONCENTRAÇÕES DE PENICILINA G. BENZATINA

open access: yesRevista da Escola de Enfermagem da USP
A procura de respostas científicas aos problemas decorrentes de procedimentos que envolvem ações profissionais constituem um desafio constante aos enfermeiros comprometidos com a melhoria do cuidado de enfermagem.
Mara Rita Rodrigues Massad   +2 more
doaj   +1 more source

Antimicrobial Activity of Penicillin G and N-acetylcystein on Planktonic and Sessile Cells of Streptococcus suis [PDF]

open access: yesPolish Journal of Microbiology, 2016
The aim of this study was to investigate the capacity of Streptococcus suis strains to form biofilms and to evaluate the antimicrobial activity of Penicillin G and N-acetylcystein (NAC) on both S. suis sessile and planktonic forms.
Ivette Espinosa   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Efficiency Evalution Ultrasonic/Fenton Process in Removal of Antibiotic Penicillin G from Aquatic Solution by Response Surface Methodology

open access: yesMuhandisī-i Bihdāsht-i Muḥīṭ, 2017
Background and Purpose: Extreme use of antibiotics and discharging them to the environment lead to serious consequences. Antibiotic Penicillin G a common antibiotic due to high production and are used in the treatment of infectious diseases  health ...
Ayat hossein panahi   +3 more
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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