Results 51 to 60 of about 931,799 (306)
ANTIBACTERIAL ACTIVITY OF CEFOPERAZONE AGAINST N.GONORRHOEAE STRAINST [PDF]
, 1983 1) 1981年8月より1982年4月までに都立台東病院で臨床分離された淋菌53株に対するcefoperazoneおよびpenicillin G, ampicillin, tetracycline, kanamycin, spectinomycinの抗菌力について検討した.2) Penicillin Gおよびampicillinでは, MIC 0.8 μg/ml以上の耐性淋菌は約60%であり, MIC 25-100 μg/ml以上を示すβ-lactamase産生淋菌も5株(9%)認められた ...
三井, 一子 +2 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Cumhuriyet Science Journal, 2020 Penicillin G, tetracycline and oxytetracycline are broad-spectrum antibiotics with considerably low side effects which are used in most of the poultries.
Fatos Ayca Ozdemir Olgun +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Muhandisī-i Bihdāsht-i Muḥīṭ, 2017 Background and Purpose: Extreme use of antibiotics and discharging them to the environment lead to serious consequences. Antibiotic Penicillin G a common antibiotic due to high production and are used in the treatment of infectious diseases health ...
Ayat hossein panahi +3 more
doaj
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
International Journal of Electrochemical Science, 2015 The inhibition performances of four penicillin derivatives, including penicillin G, oxacillin, penicillin V and amoxicillin as organic corrosion inhibitors for mild steel in 1.0 M HCl solution were investigated by weight loss measurement and Tafel ...
Yi Liang +4 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Medical treatment of staphylococcal infective endocarditis [PDF]
, 2017 Staphylococcal infective endocarditis is a severe event requiring aggressive therapy. Antibiotic regimen depends mainly on (1) the species of Staphylococcus (Staphylococcus aureus versus coagulase-negative staphylococci) and its resistance pattern ...
Bille, J.
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