Results 91 to 100 of about 270,867 (302)
مجله دانشکده پزشکی اصفهان, 2012 Background: A major concern about S. pneumoniae is the emergence of resistance to antibiotics, especially to penicillin. The aim of this study was to assess the role of PBPs gene in penicillin resistance of S.
Mohammad Kargar +2 more
doaj
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
FEBS Open Bio, EarlyView.We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Advanced Biology, EarlyView.Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav +5 more
wiley +1 more source
Nasopharyngeal carriage of penicillin-resistant Streptococcus pneumoniae in healthy children
The Turkish Journal of Pediatrics, 2007 Streptococcus pneumoniae carriage is a risk factor for the development of respiratory system infections and the spread of penicillin-resistant strains. The aim of this study was to investigate nasopharyngeal carriage of S.
Arzu Uzuner +8 more
doaj
Resistance of Escherichia coli Isolated from Water Sources on West Lombok Farms to Antibiotics
Media Kedokteran HewanAntibiotics are frequently used arbitrarily in livestock industry without regards for dosage or norms use. The administration of antibiotics to livestock can lead to a decline in their efficacy and contribute to the emergence of antibiotic resistance ...
Novarina Sulsia Ista'In Ningtyas +3 more
doaj +1 more source
Antimicrobial Titanium–Copper Alloys: The Role of Microstructure in Arc‐Melted Compositions
Advanced Engineering Materials, EarlyView.Copper‐containing titanium alloys show promise in combating orthopedic implant infections. This study explores the influence of heat treatment on Ti‐11.5Cu and Ti‐33Cu alloys, revealing that larger Ti2Cu precipitates (≈5 μm) enhance antimicrobial efficacy through increased surface contact. Results suggest contact sterilization is the primary mechanism,
Daisy Rabbitt +5 more
wiley +1 more source
Journal of Global Antimicrobial Resistance: Objectives: Streptococcus pneumoniae (S. pneumoniae) is a significant cause of global morbidity and mortality across all age groups. Antimicrobial resistance (AMR), particularly penicillin resistance, is a significant treatment challenge.
Avani Panickar +2 more
doaj
Key Trends and Insights in Smart Polymeric Skin Wearable Patches
Advanced Engineering Materials, EarlyView.Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez +2 more
wiley +1 more source
Inheritance of low-level resistance to penicillin, tetracycline, and chloramphenicol in Neisseria gonorrhoeae [PDF]
, 1975 P. Frederick Sparling +2 more
openalex +1 more source